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Órgano Oficial del Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
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2023, Number 1

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Salud Mental 2023; 46 (1)

Association of loneliness, social isolation, and daily cognitive function in Mexican older adults living in community during the first wave of COVID-19 pandemic

Durón-Reyes DE, Mimenza-Alvarado AJ, Gutiérrez-Gutiérrez L, Suing-Ortega MJ, Quiroz YT, Aguilar-Navarro SG
Full text How to cite this article

Language: English
References: 33
Page: 19-26
PDF size: 231.70 Kb.


Key words:

Loneliness, social-isolation, cognition, aged, COVID-19.

ABSTRACT

Introduction. Loneliness and social isolation are known risk factors for cognitive decline; their effect in older adults (OA) after COVID-19 lockdown is emerging. Objective. To establish an association between loneliness and social isolation, with daily cognitive function in Mexican OA during the first wave of the COVID-19 pandemic. Method. Cross-sectional study, derived from the cohort “The impact of COVID 19 on well-being, cognition, and discrimination among older adults in the United States and Latin America”, which included 308 OA recruited between March-August 2020 whose daily cognitive function were determined with the Everyday Cognition Scale (E-Cog) as dichotomized score (cut point: 1.31 for normal cognition). Loneliness and social isolation were binomial variables. Results. The mean age was 65.4 ± 7.9 years, 75.7% were women. The mean continuous E-Cog score was 57.4 (SD = ± 19.1), 49.1% had a score ‹ 1.31 (normal cognition), while 50.9% had a higher score (cognitive impairment). Eighty four percent of participants reported loneliness, 79.9% reported social isolation. Multivariate regression model showed a negative and statistically significant association between social isolation and loneliness and E-Cog, adjusted by age, sex and education level (β = -.046, 95% CI = [-.8, -.013], p = .007; β = -.16, 95% CI = [-.08, -.018], p = .003), and a positive association with subjective memory complaint (β = .81, 95% CI = [-.16, -.11], p = ‹ .001). Discussion and conclusion. These data suggest the need for increased vigilance of those who have loneliness and social isolation due to its potential deleterious effect on cognitive function.


REFERENCES

  1. Akhter-Khan, S. C., Tao, Q., Ang, T. F. A., Itchapurapu, I. S., Alosco, M. L., Mez,J., … Qiu, W. Q. (2021). Associations of loneliness with risk of Alzheimer’sdisease dementia in the Framingham Heart Study. Alzheimer’s & Dementia,17(10), 1619-1627 doi: 10.1002/alz.12327

  2. Babulal, G. M., Torres, V. L., Acosta, D., Agüero, C., Aguilar-Navarro, S., Amariglio,R., … Quiroz, Y. T. (2021). The impact of COVID-19 on the well-beingand cognition of older adults living in the United States and Latin America.EClinicalMedicine, 35, 100848. doi: 10.1016/j.eclinm.2021.100848

  3. Brailean, A., Steptoe, A., Batty, G. D., Zaninotto, P., & Llewellyn, D. J. (2019).Are subjective memory complaints indicative of objective cognitive declineor depressive symptoms? Findings from the English Longitudinal Studyof Ageing. Journal of Psychiatric Research, 110, 143-151. doi: 10.1016/j.jpsychires.2018.12.005

  4. Burns, J., Movsisyan, A., Stratil, J. M., Coenen, M., Emmert-Fees, K. M. F.,Geffert, K., ... Rehfuess, E. (2020). Travel‐related control measures to containthe COVID‐19 pandemic: a rapid review. Cochrane Database of SystematicReviews, 9, CD013717. doi: 10.1002/14651858.CD013717

  5. Bzdok, D., & Dunbar, R. I. M. (2020). The Neurobiology of Social Distance. Trendsin Cognitive Sciences, 24(9), 717-733. doi: 10.1016/j.tics.2020.05.016

  6. De Jong Gierveld, J., & Tilburg, T. Van. (2006). A 6-Item Scale for Overall,Emotional, and Social Loneliness Confirmatory Tests on Survey Data. Researchon Aging, 28(5), 582-598. doi: 10.1177/0164027506289723

  7. Domènech-Abella, J., Mundó, J., Leonardi, M., Chatterji, S., Tobiasz-Adamczyk,B., Koskinen, S., … Olaya, B. (2020). Loneliness and depression among olderEuropean adults: The role of perceived neighborhood built environment. Health& Place, 62, 102280. doi: 10.1016/j.healthplace.2019.102280

  8. Farias, S. T., Mungas, D., Reed, B. R., Cahn-Weiner, D., Jagust, W., Baynes, K., &DeCarli, C. (2008). The Measurement of Everyday Cognition (ECog): ScaleDevelopment and Psychometric Properties. Neuropsychology, 22(4), 531-544.doi: 10.1037/0894-4105.22.4.531

  9. Filshtein, T., Chan, M., Mungas, D., Whitmer, R., Fletcher, E., DeCarli, C., &Farias, S. (2020). Differential Item Functioning of the Everyday Cognition(ECog) Scales in Relation to Racial/Ethnic Groups. Journal of the InternationalNeuropsychological Society, 26(5), 515-526. doi: 10.1017/S1355617719001437

  10. Freedman, A., & Nicolle, J. (2020). Social isolation and loneliness: The new geriatricgiants Approach for primary care. Canadian Family Physician, 66(3), 176-182.

  11. Go, R. C. P., Duke, L. W., Harrell, L. E., Cody, H., Bassett, S. S., Folstein, M. F.,… Blacker, D. (1997). Development and validation of a structured telephoneinterview for dementia assessment (STIDA): The NIMH genetics initiative.Journal of Geriatric Psychiatry and Neurology, 10(4), 161-167. doi:10.1177/089198879701000407

  12. Grasso, D. J., Briggs-Gowan, M. J., Ford, J. D., & Carter, A. S. (2020). Epidemic-Pandemic Impacts Inventory (EPII).

  13. Harris, P. A., Taylor, R., Thielke, R., Payne, J., Gonzalez, N., & Conde, J. G. (2009).Research electronic data capture (REDCap)-A metadata-driven methodologyand workflow process for providing translational research informaticssupport. Journal of Biomedical Informatics, 42(2), 377-381. doi: 10.1016/j.jbi.2008.08.010

  14. Hsu, J. L., Hsu, W. C., Chang, C. C., Lin, K. J., Hsiao, I. T., Fan, Y. C., & Bai, C.H. (2017). Everyday cognition scales are related to cognitive function in theearly stage of probable Alzheimer’s disease and FDG-PET findings. ScientificReports, 7(1), 1719. doi: 10.1038/s41598-017-01193-6

  15. Kim, A. J., Beam, C. R., Greenberg, N. E., & Burke, S. L. (2020). Health Factorsas Potential Mediators of the Longitudinal Effect of Loneliness on GeneralCognitive Ability. American Journal of Geriatric Psychiatry, 28(12), 1272-1283. doi: 10.1016/j.jagp.2020.07.017

  16. Kotwal, A. A., Holt-Lunstad, J., Newmark, R. L., Cenzer, I., Smith, A. K., Covinsky,K. E., … Perissinotto, C. M. (2021). Social Isolation and Loneliness AmongSan Francisco Bay Area Older Adults During the COVID-19 Shelter-in-PlaceOrders. Journal of the American Geriatrics Society, 69(1), 20-29. doi:10.1111/jgs.16865

  17. Lara, E., Caballero, F. F., Rico-Uribe, L. A., Olaya, B., Haro, J. M., Ayuso-Mateos,J. L., & Miret, M. (2019). Are loneliness and social isolation associated withcognitive decline? International Journal of Geriatric Psychiatry, 34(11), 1613-1622. doi: 10.1002/gps.5174

  18. Leser, N., & Wagner, S. (2015). The effects of acute social isolation on long-termsocial recognition memory. Neurobiology of Learning and Memory, 124, 97-103. doi: 10.1016/j.nlm.2015.07.002

  19. Luanaigh, C. Ó., & Lawlor, B. A. (2008). Loneliness and the health of older people.International Journal of Geriatric Psychiatry, 23(12), 1213-1221. doi: 10.1002/gps.2054

  20. Marshall, G. A., Zoller, A. S., Kelly, K. E., Amariglio, R. E., Locascio, J. J., Johnson,K. A., … Rentz, D. M. (2014). Everyday Cognition Scale Items that BestDiscriminate Between and Predict Progression From Clinically Normal to MildCognitive Impairment. Current Alzheimer Research, 11(9), 853-861. doi: 10.2174/1567205011666141001120903

  21. Mumtaz, F., Khan, M. I., Zubair, M., & Dehpour, A. R. (2018). Neurobiology andconsequences of social isolation stress in animal model—A comprehensivereview. Biomedicine & Pharmacotherapy, 105, 1205-1222. doi: 10.1016/j.biopha.2018.05.086

  22. Rueda, A. D., Lau, K. M., Saito, N., Harvey, D., Risacher, S. L., Aisen, P. S., … Farias,S. T. (2015). Self-rated and informant-rated everyday function in comparisonto objective markers of Alzheimer’s disease. Alzheimer’s & Dementia, 11(9),1080-1089. doi: 10.1016/j.jalz.2014.09.002

  23. Russo, M. J., Cohen, G., Chrem Mendez, P., Campos, J., Martín, M. E., Clarens,M. F., … Allegri, R. F. (2018). Utility of the Spanish version of the EverydayCognition scale in the diagnosis of mild cognitive impairment and mild dementiain an older cohort from the Argentina-ADNI. Aging Clinical and ExperimentalResearch, 30(10), 1167-1176. doi: 10.1007/s40520-018-0899-8

  24. Savage, R. D., Wu, W., Li, J., Lawson, A., Bronskill, S. E., Chamberlain, S. A., …Rochon, P. A. (2021). Loneliness among older adults in the community duringCOVID-19: A cross-sectional survey in Canada. BMJ Open, 11(4), e044517.doi: 10.1136/bmjopen-2020-044517

  25. Secretaría de Salud México, CENAPRECE, Institución Nacional de Salud Pública,IMSS, INEGI, CONAPO, RENAPO, & Organización Panamericana de laSalud. (2020). Boletín Estadístico sobre exceso de mortalidad por todas lascausas durante la emergencia por COVID-19. Boletín Estadístico, 1(1), 1-27.

  26. Sepulveda-Loyola, W., Rodriguez-Sanchez, I., Perez-Rodriguez, P., Ganz, F.,Torralba, R., Oliveira, D. V., & Rodriguez-Mañas, L. (2020). Impact of SocialIsolation due to Covid-19 on Health in Older People: Mental and PhysicalEffects and Recommendations. Journal of Nutrition, Health and Aging, 24(2),938-947. doi: 10.1007/s12603-020-1469-2; doi: 10.1007/s12603-020-1500-7

  27. Shankar, A., Hamer, M., McMunn, A., & Steptoe, A. (2013). Social isolation andloneliness: Relationships with cognitive function during 4 years of follow-up inthe English longitudinal study of ageing. Psychosomatic Medicine, 75(2), 161-170. doi: 10.1097/PSY.0b013e31827f09cd

  28. Tomaszewski Farias, S., Mungas, D., Harvey, D. J., Simmons, A., Reed, B. R., &DeCarli, C. (2011). The measurement of everyday cognition: Developmentand validation of a short form of the Everyday Cognition scales. Alzheimer’s &Dementia, 7(6), 593-601. doi: 10.1016/j.jalz.2011.02.007

  29. Tragantzopoulou, P., & Giannouli, V. (2021). Social isolation and loneliness in oldage: Exploring their role in mental and physical health. Psychiatriki, 32(1), 59-66. doi: 10.22365/jpsych.2021.009

  30. van Harten, A. C., Mielke, M. M., Swenson-Dravis, D. M., Hagen, C. E., Edwards, K.K., Roberts, R. O., … Petersen, R. C. (2018). Subjective cognitive decline andrisk of MCI: The Mayo Clinic Study of Aging. Neurology, 91(4), e300-e312.doi: 10.1212/WNL.0000000000005863

  31. Wilkialis, L., Rodrigues, N., Majeed, A., Lee, Y., Lipsitz, O., Gill, H., … McIntyre,R. S. (2021). Loneliness-based impaired reward system pathway: Theoreticaland clinical analysis and application. Psychiatry Research, 298, 113800. doi:10.1016/j.psychres.2021.113800

  32. Wong, S. Y. S., Zhang, D., Sit, R. W. S., Yip, B. H. K., Chung, R. Y., Wong, C. K.M., ... Mercer, S. W. (2020). Impact of COVID-19 on loneliness, mental health,and health service utilisation: a prospective cohort study of older adults withmultimorbidity in primary care. British Journal of General Practice, 70(700),e817-e824. doi: 10.3399/BJGP20X713021

  33. Zovetti, N., Rossetti, M. G., Perlini, C., Brambilla, P., & Bellani, M. (2021).Neuroimaging studies exploring the neural basis of social isolation. Epidemiologyand Psychiatric Sciences, 30, e29. doi: 10.1017/S2045796021000135




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Salud Mental. 2023;46