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Boletín Clínico de la Asociación Médica del Hospital Infantil del Estado de Sonora

2023, Number 1

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Bol Clin Hosp Infant Edo Son 2023; 40 (1)

Diabetes mellitus type 1. Update

Vázquez GJA, Alonso PNC, Reyes GU, Reyes HKL, Aguilar FÉS, Pérez PO, González AA, Cuevas LLL, Álvarez SRM, Vargas VM, Quero HA, López CG

Language: Spanish
References: 19
Page: 16-20
PDF size: 172.07 Kb.


ABSTRACT

Diabetes mellitus is a group of pathologies that cause metabolic disorders in which there is an elevation of blood glucose levels, either due to a total or partial lack of insulin as a consequence of a defect in production or secretion at the level of the pancreas or by resistance to its action. The vast majority of cases are grouped into what corresponds to Type 1 Diabetes mellitus (DMT1) (5% of all cases) and is due to autoimmune destruction of β cells that leads to absolute insulin deficiency, including Latent Autoimmune Diabetes of Adulthood (LADA) and Type 2 Diabetes mellitus (T2DM) (90% of all cases). There are other types of Diabetes such as monogenic Diabetes (2-5% of all cases) (Neonatal Diabetes and Adult Onset Diabetes in Young People, MODY; Maturity Onset Diabetes of the Young) of which 13 different subvariants have been described, Diabetes of the exocrine pancreas such as cystic fibrosis and pancreatitis, diabetes induced by drugs or medications (mainly glucocorticoids), as well as gestational diabetes. This is a basic update review of type 1 diabetes mellitus for the first contact pediatrician in Primary Care.


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