Serrato RJA, Suro SY, Ruiz YJA, Fuentes HJE, Sáenz HB

Language: Spanish
References: 3
Page: 282-284
PDF size: 170.92 Kb.

ABSTRACT

Anorectal melanoma is rare, with 0.4 to 1.6% of all melanomas and 0.5% of anorectal malignancies. Frequently confused with hemorrhoidal disease and polyps. A 53-year-old female with no previous history presented with a foreign body sensation in the anal region and rectorrhagia of two months' evolution. On proctologic examination, an indurated mass was detected in the left lateral region, 4 cm from the anal margin, and an examining glove came out with hematic debris. Colonoscopy reports a 2 cm pedunculated, friable, pigmented lesion located laterally in the dentate line. He underwent a wide local transanal resection (WLTR). Pathology reports malignant melanoma, positive resection margins, and in contact with neoplastic cells. She is subsequently treated with Nivolumab and adjuvant radiotherapy. The surgical options are WLTR and abdominoperineal resection (APR). Traditionally APR was considered the best option for locoregional control of the disease. However, recent studies report no difference in survival compared to WLTR. Most patients are diagnosed late in the disease; therefore, curative surgery is impossible.

REFERENCES

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2. Malaguarnera G, Madeddu R, Catania VE, Bertino G, Morelli L, Perrotta RE et al. Anorectal mucosal melanoma. Oncotarget. 2018; 9 (9): 8785-8800.

3. Mireia MR, Carlos CS. Anal melanoma: a rare perianal tumor with a poor prognosis. Dis Colon Rectum. 2020; 63 (5): 573-576.