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Revista Médica Sinergia

2023, Number 05

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Revista Médica Sinergia 2023; 8 (05)

Role of the intestinal microbiota on renal function and its relationship with chronic kidney disease

Castro FM, Gamboa MS, Guevara SMF

Language: Spanish
References: 18
Page:
PDF size: 168.64 Kb.


ABSTRACT

The human microbiota is a complex ecosystem of microorganisms including bacteria, viruses, archaea, and fungi that inhabit the human body. Recent studies have highlighted the importance of the microbiota in different physiological processes, including metabolism, immunity and inflammation. In the context of renal function, several studies have indicated that the microbiota may play an important role in the development and progression of chronic kidney disease (CKD). This literature review article provides a comprehensive overview of the literature that focuses primarily on the relationship between the gut microbiota and CKD, and highlights gaps in this knowledge. Recent evidence supporting the notion that the microbiota has an impact on CKD is summarized, discusses the potential mechanisms of the gut-kidney axis, and discusses the therapeutic potential of strategies targeting the gut microbiota.


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