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2023, Number 2

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Rev Mex Traspl 2023; 12 (2)

Mortality risk factors in kidney transplants with COVID-19

Iñiguez-Torres S, Ortega-Cázares OA

Language: Spanish
References: 17
Page: 74-80
PDF size: 279.99 Kb.


ABSTRACT

Introduction: in the current COVID-19 pandemic, they have been reported 228'000,000 cases around the world. Patients with chronic immunosuppression, such as kidney transplants, are more susceptible to severe disease and higher mortality. Comorbidities such as diabetes, hypertension or obesity have been identified as factors associated with mortality in the general population and in solid organ transplants. Objective: to establish the relationship of risk factors with mortality during hospitalization in patients with renal transplantation who were admitted to the UMAE No. 25 for the diagnosis of COVID-19. Material and methods: case-control study, retrospective, analytical and comparative, observational. Kidney transplant patients over the age of 18 years hospitalized with the diagnosis of COVID-19 will be included. Excluding patients ruled out for their low clinical probability, as well as those who already have the diagnosis of renal graft loss. Among the variables to be related is age over 60 years, comorbidities such as diabetes, hypertension, heart disease or obesity. Analysis with 95% confidence interval. Value of p < 0.05 significant by χ2. Results: no relationship was found between the diagnosis of hypertension and/or diabetes with higher mortality, being over 60 years old was related as a risk factor for mortality, although without statistical significance. Requiring mechanical ventilation, critical illness and hyperkalemia were associated with higher mortality being statistically significant. Conclusion: no relationship was found between mortality and comorbidities; however, it was not statistically significant.


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