2023, Number 1
Blood markers are related to severity and requiring of mechanic ventilation in hospitalized patients due to COVID-19
García-Suárez A, López-Vilchis LE, Solorio-Rivera AH, Rivera-Trujillo A, Carranza-Madrigal J
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Language: Spanish
References: 9
Page: 8-14
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ABSTRACT
Objective: To determine the association between blood markers and severity due to COVID-19.Materials and Methods: Observational, analytical, case-control, retrospective, cross-sectional study was done with records of hospitalized patients with COVID-19 with positive RT-PCR from January 1st, 2021 to December 31st, 2021. Descriptive and analytical statistics were obtained, measures of central tendency were used and other methods such as Student’s t-test to compare continuous numerical variables and χ2 for categorical variables.
Results: Of 687 files reviewed, most patients were male, with a mean age of 56.4 years; all blood marker variables such as leukocyte alterations, D-dimer, C-reactive protein, ferritin and hemotype were associated with a greater probability of requiring invasive mechanical ventilation and death.
Conclusions: In COVID-19 patients with positive RT-PCR requiring hospitalization for ventilatory support, altered levels of leukocytes, D-dimer, C-reactive protein and serum ferritin are strongly associated with an increased risk of requiring invasive mechanical ventilation and death.
REFERENCES
Triggle CR, Bansal D, Ding H, Islam MM, Farag E, Hadi HA,Sultan AA. A comprehensive review of viral characteristics,transmission, pathophysiology, immune response, andmanagement of SARS-CoV-2 and COVID-19 as a basis forcontrolling the pandemic. Frontiers Immunol 2021; 12:631139. https://doi.org/10.3389/fimmu.2021.631139.