medigraphic.com
SPANISH

Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2023, Number 07

<< Back Next >>

Ginecol Obstet Mex 2023; 91 (07)

Metastatic sarcomatosus squamous carcinoma to the placenta: a case report

Castilla GJE, Espinoza MS, Garrido RD, Revilla CME, Saldaña DC
Full text How to cite this article

Language: Spanish
References: 12
Page: 527-533
PDF size: 408.90 Kb.


Key words:

Sarcomatoid cutaneous epidermoid cancer, Placenta, Squamous cell carcinoma, Amputation, Sarcoma, Cesarean section.

ABSTRACT

Background: Sarcomatoid cutaneous epidermoid cancer is a rare neoplasm, with a low risk of malignancy and less than 2% risk of metastasis. Its aggressive behavior is unusual and almost always associated with factors favoring its malignancy. Placental metastasis is also exceptional: only 61 cases have been reported to date.
Clinical case: 35-year-old female patient, with a history of two pregnancies, in 33 weeks of gestation, infiltrating squamous cell carcinoma of the left leg, with supracondylar amputation and pulmonary metastasis. She was admitted to the emergency room for respiratory distress, without labor, tachycardic and tachypneic. It was decided to perform a cesarean section with live birth, female, 1860 g, without complications. After the intervention, the patient was transferred to an institution specialized in oncologic care, where she died 24 hours later. The newborn was discharged without complications and without oncologic or other manifestations up to one year of age.
Conclusions: After an exhaustive search of the literature, the authors consider the case reported here to be the first case of sarcomatoid epidermoid skin cancer with metastasis to the placenta.


REFERENCES

  1. Valdeolivas-Casillas N, Polo-Rodríguez I, Medina-MontalvoMS, Vélez MD, Cabrera-Hernández A, García-RodríguezMM. Carcinoma epidermoide cutáneo de células fusiformesmetastásico. Med Cutánea Ibero-Lat-Am 2016; 43(S1): 41-4. https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=67393

  2. Kallini JR, Hamed N, Khachemoune A. Squamous cellcarcinoma of the skin: epidemiology, classification, management,and novel trends. Int J Dermatol 2015; 54 (2):130-40. https://doi.org/10.1111/ijd.12553

  3. Waldman A, Schmults C. Cutaneous Squamous Cell Carcinoma.Hematol Oncol Clin North Am 2019; 33 (1): 1-12.https://doi.org/10.1016/j.hoc.2018.08.001

  4. Martorell-Calatayud A, Sanmartín Jimenez O, Cruz MojarrietaJ, Guillén Barona C. Carcinoma epidermoidecutáneo: definiendo la variante de alto riesgo. ActasDermo-Sifiliográficas 2013; 104 (5): 367-79. https://doi.org/10.1016/j.ad.2011.12.019

  5. Shah BJ, Tupkari JV, Joy T. Sarcomatoid squamous cell carcinomaof mandible: A report of two cases. JOMFP 2019;23 (1): 163. https://doi.org/10.4103/jomfp.JOMFP_237_18

  6. Viswanathan S, Rahman K, Pallavi S, Sachin J, Patil A, ChaturvediP, et al. Sarcomatoid (spindle cell) carcinoma of thehead and neck mucosal region: a clinicopathologic reviewof 103 cases from a tertiary referral cancer centre. HeadNeck Pathol 2010; 4 (4): 265-75. https://doi.org/10.1007/s12105-010-0204-4

  7. Andersson TML, Johansson ALV, Fredriksson I, Lambe M.Cancer during pregnancy and the postpartum period: Apopulation-based study. Cancer 2015; 121 (12): 2072-7.https://doi.org/10.1002/cncr.29325

  8. Sebire NJ, Jauniaux E. Fetal and placental malignancies: prenataldiagnosis and management. Ultrasound Obstet Gynecol2009; 33 (2): 235-44. https://doi.org/10.1002/uog.6246

  9. Khazzaka A, Rassy E, Sleiman Z, Boussios S, Pavlidis N.Systematic review of fetal and placental metastasesamong pregnant patients with cancer. Cancer TreatRev 2022; 104: 102356. https://doi.org/10.1016/j.ctrv.2022.102356

  10. Cassarino DS, Derienzo DP, Barr RJ. Cutaneous squamouscell carcinoma: a comprehensive clinicopathologic classification.Part one. J Cutan Pathol 2006; 33 (3): 191-206.https://doi.org/10.1111/j.0303-6987.2006.00516.x

  11. Lyakhovitsky A, Barzilai A, Fogel M, Trau H, Huszar M.Expression of e-cadherin and beta-catenin in cutaneoussquamous cell carcinoma and its precursors.Am J Dermatopathol 2004; 26 (5): 372-8. https://doi.org/10.1097/00000372-200410000-00005

  12. Motley R, Kersey P, Lawrence C, British Association ofDermatologists, British Association of Plastic Surgeons,Royal College of Radiologists, Faculty of Clinical Oncology.Multiprofessional guidelines for the management of thepatient with primary cutaneous squamous cell carcinoma.Br J Dermatol 2002; 146 (1): 18-25. https://doi.org/10.1046/j.0007-0963.2001.04615.x




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Ginecol Obstet Mex. 2023;91