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2023, Number 4

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Med Crit 2023; 37 (4)

PaO2/FiO2/PEEP ratio as a predictor of mortality in COVID-19 patients

Ramos EMS, Muñoz RMR

Language: Spanish
References: 11
Page: 342-347
PDF size: 219.27 Kb.


ABSTRACT

Introduction: there is an urgent need to identify prognostic factors, both clinical and paraclinical, that allow patient risk stratification and active control of COVID-19. In our setting, there have been no published studies evaluating the PaO2 /FiO2 /PEEP (P/F/PEEP) index as a predictor of mortality in COVID-19 patients. Objective: to determine if the PaO2/FiO2/PEEP index acts as a factor associated with mortality in COVID-19 patients. Material and methods: retrospective, analytical and cross-sectional study in patients diagnosed with severe COVID-19. Results: lower values were identified for the PaO2/FiO2 index among the cases that died: 143.23 ± 76.54 vs 162.79 ± 64.86 in the survivors, however, there was no significance (p = 0.263). In the PaO2/FiO2/PEEP index, the differences also decreased between the cases that died 140.27 ± 94.78 vs the survivors 191.25 ± 108.7 (p = 0.030). Conclusions: the PaO2/FiO2/PEEP index is a predictor of mortality in COVID-19 patients, it is significantly associated with an AUC higher than the PaO2/FiO2 index to predict mortality at a cut-off point of ≤ 80 as a mortality factor with a good specificity and high sensitivity.


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