2003, Number s1
Next >>
Rev Mex Pediatr 2003; 70 (s1)
New evidences about the ampicilina effectiveness in bacterial pharyngoamygdalitis. A multicentric study
Adell A, Abraham JAE, Calva R, Hernández P, López A, Nesbitt C, Novales X, Novoa O, Ochoa M, Rodríguez A, Rodríguez TJ, Rodríguez M, Serrano A, Sotelo N, Tristán J, Yamamoto FJK, Granados J
Language: Spanish
References: 13
Page: 3-6
PDF size: 80.07 Kb.
ABSTRACT
Objective. To study the ampicilin effectiveness in the treatment of the bacterial pharyngoamygdalitis in children.
Material and methods. 11,866 children with the clinical diagnostic of bacterial pharyngoamygdalitis were studied in 120 cities of Mexico. All of them received ampicillin: 50 mg/kg of weight, in three dose per day. The smaller than 20 kg body weight received 250 mg three times a day, and those that had among 20 to 30 kg body weight: 500 mg three times a day. The treatment was given for seven to ten days. The clinical response to the treatment was evaluated.
Result. The response to the treatment was quite satisfactory in 92% children’s and fail in 6.7%. The frequency of adverse manifestations due to ampicillin did not motivate change in the treatment.
Conclusion. The use of ampicilin in children with pharyngoamygdalitis give a good clinical response. In this study there was a reduced frequency of adverse effects.
REFERENCES
Seppala H, Nissinem A, Jarvinen H, Huovinen S, Hennriksson T, Herva E et al. Resistance to erythromycin in group A Streptococci. N Engl J Med 1992; 326: 292-7.
York MK, Gibss L, Perdrean-Remington F, Brooks GF. Characterization of antimicrobial resistance in Streptococcus pyogenes isolates from the San Francisco Bay area of Northern California. J Clin Microbiol 1999; 37: 1727-31.
Vargas-Catalán N, Díaz AP, Zuleta QA, López BIM, Venegas-Silva V. Cuidado en sala de cuna: impacto sobre la patología respiratoria aguda baja del menor de 2 años. Rev Med Chile 1994; 122: 836-42.
Nafstad P, Hagen JA, Oie L, Magnus P, Jaakkola JJ. Day care centers and respiratory health. Pediatrics 1999; 103(4): 753-758.
Sodestrom M, Hovelius B, Prellner K. Respiratory tract infections in children with recurrent episodes as preschoolers. Acta Paediatr Scand 1991; 80: 688-695.
Wannamaker LW. Perplexity and precision in the diagnosis of streptococcal pharyngitis. Am J Dis Child 1972; 14: 352-8.
Kaplan EL, Top FH Jr, Dudding BA, Wannamaker LW. Diagnosis of Streptococcal pharyngitis: differentiation of active infection from de carrier state in the symptomatic child. J Infect Dis 1971; 123: 490-501.
Bisno AL. Acute Pharyngitis. N Engl J Med 2001; 344: 205-11.
Adell GA, Cicero R, Coca J, Fernández M, Hernández AJ, Michel P y cols. Prevalencia de gérmenes causantes de faringoamigdalitis. Sensibilidad y respuesta terapéutica a la ampicilina. Rev Enf Infec Pediatr 1998; 11: 188-92.
Bisno AL, Gerber MA, Gwaltney JM, Kaplan EL, Schwatz RH. Practice Guidelines for the Diagnosis and Management of Group A Streptococcal Pharyngitis. Clin Infect Dis 2002; 35: 113-25.
Schwartz B, Marcy SM, Phillips WR, Gerber MA. Pharyngitis: Principles of judicious use of antimicrobial agents. Pediatrics 1998; 101: 171-4.
Calderón-Jaimes E. Indicaciones terapéuticas de las penicilinas en las infecciones respiratorias. Boletín Médico del Hospital Infantil de México 2002; 59: 568-83.
Rodríguez RS, Calderón-Jaimes E, Gómez BD, Espinosa-de los Monteros LE. Características de la resistencia antimicrobiana de una colección clínica de Streptococcus pyogenes. Salud Pública Mex 2000; 42: 226-9.