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Revista de Nefrología, Diálisis y Trasplante

ISSN 0326-3428 (Print)
Órgano de difusión científica de la Asociación Nefrológica de Buenos Aires
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2023, Number 3

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Rev Nefrol Dial Traspl 2023; 43 (3)

Acute encephalopathy due to severe hypophosphatemia

López-González-Gila JD, Rosales-Castillo A, Aguilar-Jaldo MP, Mañero-Rodríguez CA
Full text How to cite this article

Language: Spanish
References: 10
Page: 180-183
PDF size: 147.70 Kb.


Key words:

hypophosphatemia, acute encephalopathy, hospitalization, tubule, redistribution.

ABSTRACT

Hypophosphatemia is a rare ionic alteration that occurs mainly in hospitalized patients. It is estimated that up to 5 percent of them may have low serum phosphate concentrations (less than 2.5 mg / dL [0.80 mmol / L]). However, prevalences greater than 30 to 50 percent have been reported in alcoholic patients and/or patients with severe sepsis or trauma. When combined with phosphate depletion (that is, when it is not due solely to phosphate movement into cells), hypophosphatemia can cause a variety of signs and symptoms, primarily symptomatic when it is less than 1 mg / dL. The leading causes are divided into four points according to their production mechanism: internal redistribution, decreased intestinal absorption, increased urinary excretion, or elimination through renal replacement techniques. We present the case of a patient suffering from unspecific acute encephalopathic symptoms associated with severe hypophosphatemia with adequate evolution after its correction.


REFERENCES

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Rev Nefrol Dial Traspl. 2023;43