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2023, Number 1

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Arch Inv Mat Inf 2023; 14 (1)

Systemic lupus erythematosus in pediatrics. Case report and literature review

Anaya-Rodríguez AK, Cortéz-Salinas MP, García-Sparza AT, Pérez EAA, Solano-Ugalde AP, González-Sánchez RM
Full text How to cite this article 10.35366/113548

DOI

DOI: 10.35366/113548
URL: https://dx.doi.org/10.35366/113548

Language: Spanish
References: 11
Page: 35-40
PDF size: 189.12 Kb.


Key words:

systemic lupus erythematosus, lupus, systemic lupus.

ABSTRACT

Introduction: systemic lupus erythematosus (SLE) is a multisystem chronic autoimmune disease of variable course. The presence of circulating autoantibodies is one of the main characteristics of the disease, these are largely responsible for the resulting inflammation. Clinical case: a 9-year-old female patient, with a three-week history of maculopapular lesions in the malar region, high fever that is difficult to control, generalized bone pain, asthenia, adynamia, glossitis, cheilosis, pharyngitis, strawberry tongue. In laboratory tests, systemic inflammation markers were found to be elevated: ESR 20 mm/h, C-reactive protein 0.7 mg/dL, D-dimer 1,120 ng/dL, ferritin 1,887 ng/mL, procalcitonin 0.64 ng/mL; low complement values: C3 25 mg/dL, C4 4.4 mg/dL; experienced antinuclear (ANA's) positive (1:320 fine speckled pattern) and experienced anti-DNA positive (greater than 800 IU/mL); confirming the diagnosis of SLE. Conclusions: it is important to suspect and suffer from this disease in a timely manner, through a meticulous anamnesis and a detailed clinical exercise, to start an opportune treatment and thus prevent pediatric patients from getting worse, the integrity of their organs can be maintained, and ensure a good quality of life in the long term.


REFERENCES

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  2. Merino-Muñoz R, Remesal-Camba A, Murias-Loza S. Lupus eritematoso sistémico. An Pediatr Contin. 2013; 11 (2): 89-97.

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  5. Coronado-Alvarado CD, Gámez-Saiz IL, Sotelo-Cruz N. Características clínicas y comorbilidades de pacientes con lupus eritematoso sistémico en niños y adultos. Acta Pediatr Mex. 2018; 39 (1): 1-12.

  6. González-Jiménez D, Mejía-Bonilla S, Cruz-Fallas M. Lupus eritematoso sistémico: enfoque general de la enfermedad. Rev Med Sinergia. 2021; 6 (1): e630.

  7. Acosta-Colman I, Avila G, Acosta ME, Aquino A, Centurión O, Duarte M. Manifestaciones clínicas y laboratoriales en el Lupus Eritematoso Sistémico-LES. Mem Inst Investig Cienc Salud. 2016; 14 (1): 94-109.

  8. Aringer M, Costenbader K, Daikh D, Brinks R, Mosca M, Ramsey-Golman R et al. 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus. Ann Rheum Dis. 2019; 78 (9): 1151-1159.

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Arch Inv Mat Inf. 2023;14