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2023, Number 4

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Rev Mex Traspl 2023; 12 (4)

Behavior of creatinine in relation to the combination of the sexes of the recipient with the donor a year after the kidney transplantation in a cohort in Mexico

Bravo-Rojas FM, Espinoza-Pérez R, Cancino-López JD, Liévano-Trejo M, Luna-Peña E, Martínez-Badajoz A, Salgado-Romano DM, González-Jiménez YE, Portuguez-Peláez R, Salas-Palomino IA, Hernández-Rivera JCH

Language: Spanish
References: 24
Page: 188-192
PDF size: 233.47 Kb.


ABSTRACT

Introduction: the behavior of creatinine is dependent on multiple factors, including the type of donor, immediate function, age of the couple, and compatibility, among others. Objective: the objective of this study is to analyze the relationship that exists between the sex of the binomial with the behavior of creatinine one year after the kidney transplant. Material and methods: kidney transplant cohort from 2014 to 2019 in Mexico. 805 patients who completed 12 months of follow-up were analyzed to assess the behavior of creatinine. For this, measures of central tendency and dispersion, frequencies, and percentages were used; For the difference between the groups, chi-square was used with a comparison of proportions per column and Kruskal-Wallis with U-Mann-Whitney, with a significant value p < 0.05. Results: the highest median creatinine was observed in male recipients of female donors with 1.29 mg/dL, 25-75 interquartile range (25-75 IQR): 1.10 to 1.50 mg/dL, followed by male recipients of males with a median of 1.24. mg/dL (25-75 IQR: 1.02 to1.50 mg/dL), then female recipients of female donors with 1.09 mg/dL (25-75 IQR: 0.90 to 1.38 mg/dL), and finally female recipients of male donors with median of 1.00 mg/dL (25-75 IQR: 0.80 to 1.23 mg/dL). Conclusion: the creatinine values in the context of the combination of the sexes lead us to think that they are dependent on the transplanted nephron mass, but also on the muscle mass of the renal recipient.


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