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2023, Number 2

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Rev Hematol Mex 2023; 24 (2)

Lymphoblastic leukemia secondary to lymphoblastic lymphoma with development of bone marrow aplasia post-induction of Hyper-CVAD

Ulloa PJJ, Juan LCLE
Full text How to cite this article

Language: Spanish
References: 10
Page: 106-111
PDF size: 289.01 Kb.


Key words:

Lymphoblastic lymphoma, Acute lymphoblastic leukemia, Induction chemotherapy.

ABSTRACT

Background: Secondary leukemias are broadly defined as a group of cancers that arise after the existence of a previous malignant neoplasm or in patients previously treated with cytotoxic therapy, that is, chemotherapy or radiotherapy.
Clinical case: A 32-year-old male patient with lymphoblastic lymphoma who received 8 cycles of chemotherapy with subsequent development of secondary acute lymphoblastic leukemia, requiring initiation of a remission induction chemotherapy scheme based on Hyper-CVAD, developing secondary bone marrow aplasia.
Conclusions: Secondary lymphoblastic leukemias are a poorly characterized condition due to limited literature and the absence of therapeutic protocols.


REFERENCES

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C?MO CITAR (Vancouver)

Rev Hematol Mex. 2023;24