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2023, Number 6

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Acta Pediatr Mex 2023; 44 (6)

Morbidity in newborns conceived with the help of assisted reproductive techniques

Bazán GS, Oldak SD, Pérez TJG, Benítez CKL
Full text How to cite this article

Language: Spanish
References: 32
Page: 432-439
PDF size: 234.07 Kb.


Key words:

Assisted reproductive techniques, Newborn Diseases, congenital abnormalities.

ABSTRACT

Objective: To report morbidity in newborns conceived using any assisted reproductive technique.
Materials and Methods: Observational, retrospective cohort study conducted by analysing the records of women who underwent assisted reproductive techniques in a private tertiary hospital between October 2016 and December 2018. The records of their respective newborns were reviewed for conditions diagnosed at birth and up to hospital discharge.
Results: Sixty-nine mothers and 95 neonates were studied. The mean age of the mothers was 36.9 years (range: 19 to 54 years). In 85.5% (59 of 69) at least one pregnancyrelated medical history was found, mainly hypothyroidism (n = 9) and myomectomy (n = 7) as a surgical procedure. Thirty-seven per cent (n = 26) of the pregnancies were twins. The mean gestational age of the newborns was 35.8 weeks (range 25.5 and 40.1); the mean birth weight was 2298 grams (range 780 and 4150 g). Birth morbidity was reported in 69 of the 95 newborns (72.6%): prematurity (84.1%), hyperbilirubinaemia (36.2%), and respiratory distress syndrome (28.9%). 20% of the newborns required admission to the intensive care unit, mainly because of prematurity (18.9%) and respiratory distress syndrome (13.6%). The mean hospital stay was 11.3 days (limits: 2 and 100), and no deaths were recorded.
Conclusions: There was a high incidence (37%) of twin pregnancies and prematurity (84.1%); in most cases the morbidity was transient, with no permanent sequelae or deaths in the neonates studied.


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Acta Pediatr Mex. 2023;44