medigraphic.com
ISSN 1561-3054 (Electronic)

2022, Number 1

<< Back Next >>

Rev Cubana Med Trop 2022; 74 (1)

Importance of african trypanosomiasis for Cuba

Menéndez CRL

Language: Spanish
References: 27
Page:
PDF size: 688.00 Kb.


ABSTRACT

Introduction: Human African trypanosomiasis is produced by protozoa of the genus Trypanosoma and transmitted mainly by the bite of the tsetse fly. There have been several epidemics in Africa in the last century, but as the number of new reported trypanosomiasis cases has decreased, the WHO roadmap for neglected tropical diseases had targeted their elimination as a public health problem by 2020. Many of the countries where Cuba provides internationalist collaboration are endemic, so the collaborators are exposed to the risk of suffering and facing this disease.
Objectives: To carry out a clinical and epidemiological update of the entity and warn about the possibility of the appearance in endemic areas and the presence of imported cases in Cuba.
Methods: a bibliographic review was carried out in the Medline / Pub Med database and in relevant articles related to the subject, from recent years; we have taken the 2020 WHO African Trypanosomiasis descriptive notes as a reference, as well as classic internal medicine texts and the ClinicalKey search platform.
Information, Analysis and Synthesis: A detailed exposition of the disease and the therapeutic behavior was made; a brief review of imported cases and the country of origin, in addition to the danger posed by the appearance of imported cases for Cuba. Conclusions: This is a potentially fatal entity, endemic in countries where there is Cuban collaboration. It is necessary to bear in mind the diagnosis of this disease for an adequate therapeutic approach.


REFERENCES

  1. OMS. La tripanosomiasis africana (enfermedad del sueño). Ginebra: OMS; Nota descriptiva enero de 2017. [Acceso 14/07/2020]. Disponible en: Disponible en: http://www.who.int/mediacentre/factsheets/fs259/es/

  2. Richard D. Tripanosomiasis africana (enfermedad del sueño africana). [Monografía en Internet] Última modificación mayo 2019. [Acceso 14/07/2020]. Disponible en: Disponible en: http://www.msdmanuals.com/es/professional/enfermedades-infecciosas/protozoos-extraintestinales/tripanosomiasis-africana

  3. OMS. La tripanosomiasis africana (enfermedad del sueño). Ginebra: OMS; Nota descriptiva 17 de febrero de 2020. [Acceso 14/07/2020]. Disponible en: Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/trypanosomiasis-human-african-(sleeping-sickness)

  4. Kirchhoff LV. Agentes de la tripanosomiasis africana (enfermedad del sueño). En Mandell, Douglas y Bennett, eds. Enfermedades infecciosas. Principios y práctica. 7.aed. Barcelona: Elsevier; 2012. p. 3487-92.

  5. Kirchhoff LV. Trypanosomiasis. In Fauci AS, Kasper DL, eds. Harrison’s Infectious Diseases. 17th ed. New York: McGraw-Hill Medical; 2010. p. 1114-17.

  6. Quinn TC. African trypanosomiasis (Sleeping sickness). Chapter 367. In Goldman and Ausiello, eds. Cecil Medicine [CD-ROM]. 23rd ed. Philadelphia: Saunders Elsevier; 2007.

  7. Petri WA. African sleeping sickness. Chapter 354. In Goldman and Schafer, eds. Cecil Medicine. 23rd ed. Philadelphia: Saunders Elsevier; 2012. p. 2018-21.

  8. Menéndez Torres O, Cá G. Tripanosomiasis africana. Presentación de un caso. MediCiego. 2003[Acceso 19/10/2019];99(5). Disponible en: Disponible en: http://www.bvs.sld.cu/revistas/mciego/vol5_supl1_99/casos/_v5_supl199.htm

  9. Franco JR, Cecchi G, Priotto G, Paone M, Diarra A, Grout L, et al. Monitoring the elimination of human African trypanosomiasis at continental and country level: Update to 2018. PLoS Negl Trop Dis. 2020;14(5):e0008261. DOI: https://doi.org/10.1371/journal.pntd.0008261

  10. Krishna S, Stich A. African tripanosomiasis: Clinical manifestations, diagnosis, and treatment. Up-to-date (Pediatric drug information). In Waltham MA. Wolters Kluwer Health Clinical Solutions. 2020. [Acceso 20/02/2021]. Disponible en: Disponible en: https://www.uptodate.com

  11. Clinical guidelines and Treatment Manual (Médecins Sans Frontières), Capítulo 6: Enfermedades parasitarias Tripanosomiasis humana africana (enfermedad del sueño). [Monografía en Internet]. Abril de 2021. [Acceso 30/08/2020]. Disponible en: Disponible en: https://medicalguidelines.msf.org/viewport/CG/latest/tripanosomiasis-humana-africana-enfermedad-del-sueno-23443044.html

  12. Soraires Santacruz MC. Síntesis, evaluación biológica y estudios computacionales de tiosemicarbazonas de 1-indanonas N4-aril sustituidas como potenciales antivirales y antiparasitarios. [Tesis Doctoral]. Buenos Aires: Facultad de Farmacia y Bioquímica. Universidad de Buenos Aires; 2019. [Acceso 30/08/2020]. Disponible en: Disponible en: https://ri.conicet.gov.ar/bitstream/handle/11336/83635/CONICET_Digital_Nro.47ad8de3-0de8-4199-90e9-9c97a50fd0ba_A.pdf?sequence=2&isAllowed=y

  13. Matteoni J. ¿Es posible la eliminación de la enfermedad del sueño en África Central y Occidental? [Tesis de Grado en Farmacia]. Canarias: Universidad de La Laguna; 2020 . [Acceso 20/06/2021]. Disponible en: Disponible en: https://riull.ull.es/xmlui/bitstream/handle/915/20467/%C2%BFEs%20posible%20la%20eliminacion%20de%20la%20enfermedad%20del%20sueno%20en%20Africa%20Central%20y%20Occidental.pdf?sequence=1

  14. Kennedy PGE. Diagnosing central nervous system trypanosomiasis: two stage or not to stage? Transactions of the Royal Society of Tropical Medicine and Hygiene. 2008;102(4):306-7. DOI: https://doi.org/10.1016/j.trstmh.2007.11.011

  15. Cecchi G, Paone M, Feldmann U, Vreysen MJB, Diall O, Mattioli RC. Assembling a geospatial database of tsetse-transmitted animal trypanosomosis for Africa. Parasites & Vectors. 2014[Acceso 30/08/2020];7:39. Disponible en: Disponible en: http://www.parasitesandvectors.com/content/7/1/39

  16. Bessell PR, Lumbala C, Lutumba P, Baloji S, Biéler S, Ndung’u JM. Cost-effectiveness of using a rapid diagnostic test to screen for human African trypanosomiasis in the Democratic Republic of the Congo. PLoS One. 2018 [Acceso 20/02/2021];13(9):e0204335. Disponible en: Disponible en: https://pubmed.ncbi.nlm.nih.gov/30240406/

  17. Lumbala C, Biéler S, Kayembe S, Makabuza J, Ongarello S, Ndung’u JM. Prospective evaluation of a rapid diagnostic test for Trypanosome brucei gambiense infection developed using recombinant antigens. PLoS Negl Trop Dis. 28 de marzo de 2018. [Acceso 20/02/2021];12(3):e0006386. Disponible en: Disponible en: https://pubmed.ncbi.nlm.nih.gov/29590116/

  18. Bouteille B, Mpandzou G, Cespuglio R. Cerebrospinal fluid B lynmphocyte identification for diagnosis and follow-up in human African trypanosomiasis in the field. Trop Med Int Health. 2010 Apr;15(4):454-61. DOI: https://doi.org/10.1111/j.1365-3156.2009.02400.X

  19. Arponen S. Tripanosomiasis africana. [Monografía en Internet] Actualizado 22 de abril de 2021. [Acceso 19/05/2021]. Disponible en: Disponible en: https://www.webconsultas.com/salud-al-dia/tripanosomiasis-africana/tratamiento-y-prevencion-de-la-tripanosomiasis-africana

  20. Büscher P, Cecchi G, Jamonneau V. Human African trypanosomiasis. Lancet. 2017;(10110):2397-409. DOI: https://doi.org/10.1016/S0140-6736(17)31510-6

  21. MacGregor P, Gonzalez-Munoz AL, Fatoumatta J, Taylor MC, Steven R, Sandercock AMl. A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis. PLoS Negl Trop Dis. 2019 May; 13(5): e0007373. DOI:https://doi.org/10.1371/journal.pntd.0007373

  22. Deeks ED. Fexinidazole: First Global Approval. Drugs. 2019 Feb;79(2):215-20. DOI: https://doi.org/10.1007/s40265-019-1051-6

  23. Fairlamb AH. Fexinidazole for the treatment of human African trypanosomiasis. Drugs Today. 2019 Nov;55(11):705-12. DOI: https://doi.org/10.1358/dot.2019.55.11.3068795

  24. Díaz Jidy M, Rodríguez Justiz F, Millán Marcelo JC, Hadad Meléndez P. Tripanosomiasis africana. Presentación de 2 casos. Rev Cub Med Militar. 1990;4(1):17-8.

  25. Ruiz JA, Simarro PP, Josenando T. Control de la tripanosomiasis humana africana en el foco de Quiçama (Angola). Bull World Health Organ. 2002[Acceso 19/08/2019];80(9):738-45. Disponible en: Disponible en: https://scholar.google.com.cu/scholar?q=bull+world+health+organ+2002+(80).9:738&hl=es&as_sdt=0&as_vis=1&oi=scholart#d=gs_qabs&u=%23p%3DmDf9lagZGb4J

  26. Steinmann P, Stone CM, Sutherland CS, Tanner M, Tediosi, F. Contemporary and emerging strategies for eliminating human African trypanosomiasis due to Trypanosoma brucei gambiense: review. Tropical Medicine & International Health. 2015 Jun;20(6):707-18. DOI: https://doi.org/10.1111/tmi.12483

  27. Mitashi P, Hasker E, Mbo F, Van Geertruyden JP, Kaswa M, Lumbala C, et al. Integration of diagnosis and treatment of sleeping sickness in primary healthcare facilities in the Democratic Republic of the Congo. Tropical Medicin e & International Health. 2015 Jan;20(1):98-105. DOI: https://doi.org/10.1111/tmi.12404




2020     |     www.medigraphic.com