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2023, Number 4

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Enf Infec Microbiol 2023; 43 (4)

Hydrogen peroxide efficacy to carry out hospital environmental decontamination

Galván CR, Valencia SJ, Lozano MKE, Villegas MI, Cabrera SCE, Luna GR, Segura CE, Villeda GG, Solórzano SF
Full text How to cite this article

Language: Spanish
References: 11
Page: 144-150
PDF size: 348.39 Kb.


Key words:

hydrogen peroxide, silver, decontamination, disinfection, sterilization, infections associated with health care.

ABSTRACT

The hospital environment favors a high risk of dissemination of microorganisms. It is necessary to include different strategies to prevent such infections. Among new cleaning techniques hydrogen peroxide has been proposed.
Material and Methods.Cross-sectional, analytical and prospective study. Total of 25 samples prior to decontamination and 25 samples after the same process with 5% hydrogen peroxide and 0.01% silver. For the evaluation, the McNemar test was used.
Results. In 23/25 samples the absence of microorganisms was obtained (without post-intervention development), with 92% (p ‹0.0001) negativity at 48 hours and in 2/20 (8%) of the samples the same bacteria development was maintained.
Conclusion. Decontamination with hydrogen peroxide and silver in closed spaces, using specialized spray equipment for 10 minutes of exposure, was effective in reducing and eliminating the bacterial load on hospital surfaces; however, it does not replace the conventional cleaning technique.


REFERENCES

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  3. Rutala, W., Gergen, M. y Weber, D., “Room decontaminationwith uv radiation”, Infect Control Hosp Epidemiol,2010, 31 (10): 1025-1029.

  4. Rutala, W.A., Weber, D.J. et al., “Guideline for disinfectionand sterilization in healthcare facilities”, 2008 [actualizadaen 2019) cdc, Disponible en: https://www.cdc.gov/infectioncontrol/guidelines/disinfection/.

  5. Hernández Navarrete, M.J., Celorio Pascual, J.M.,Lapresta Moros, C. y Solano Bernad, V.M., “Fundamentosde antisepsia, desinfección y esterilización”, EnfermedadesInfecciosas y Microbiología Clínica, 2014, 32(10): 681-688.

  6. John, M.B., Guercia, K.A., Sullivan, L., Havill, N.L., Fekieta,R., Kozakiewicz, J. et al., “Prospective clustercontrolled crossover trial to compare the impact of animproved hydrogen peroxide disinfectant and a quaternaryammonium-based disinfectant on surface contaminationand health care outcomes”, Am J Infect Control,2017, 45 (9): 106-110.

  7. Khandelwal, A., Lapolla, B., Bair, T., Grinstead, F., Hislop,M., Greene, C. y Bigham, M.T., “Enhanced disinfectionwith hybrid hydrogen peroxide fogging in a critical caresetting”, bmc Infect Dis, 2022, 22 (1): 758.

  8. Equipos Médicos Vizcarra, Sistema de desinfeccióncon peróxido de hidrógeno al 5% y plata al 0.01%, Ciudadde México, 2022.

  9. Unger-Bimczok, B., Kottke, V., Hertel, C. y Rauschnabel,J., “The influence of humidity, hydrogen peroxideconcentration, and condensation on the inactivation ofGeobacillus stearothermophilus spores with hydrogenperoxide vapor”, J Pharmaceutical Innovation, 2008, 3:123-133.

  10. Bioquell, Ecolab, Ecolablifescience, 2020 Disponibleen: https://www.bioquell.com/covid-19-and-bioquell/#emerging-pathogens.

  11. Euro Lab, “Vapor de peróxido de hidrógeno frenteal covid-19, 2020. Disponible en: https://eurolab.es/bioseguridad-sanitaria/biodescontaminacion-por-peroxido-de-hidrogeno/tecnologia-de-peroxido-de-hidrogeno-en-vapor-hpv/.




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Enf Infec Microbiol. 2023;43