Mancera RMI, Hernández RD, Bracho BE, Portela OJM, García HLA

Language: Spanish
References: 15
Page: 34-39
PDF size: 156.25 Kb.

ABSTRACT

Introduction: there are currently various neuromuscular blockers for intubation; one of them, succinylcholine, which, although it has a rapid onset of action, its adverse effects have favored the use of other NMBs such as rocuronium. Current options to minimize intubation times include the use of priming or priming. Material and methods: fifty patients under general anesthesia for orthopedic or abdominal surgery at Hospital Angeles Pedregal were studied. They were randomized into two groups (experimental and control). The control group received a rapid sequence induction dose of rocuronium and the experimental group a priming dose. Time to TOF of 0 and NMB recovery were measured. Descriptive statistics were performed using frequencies and percentages for nominal variables and measures of central tendency for quantitative variables depending on the distribution of the data. The comparison between groups was using χ² and Student's t or Mann-Whitney U. Results: both groups were homogeneous for the epidemiological variables. When comparing the experimental group against the control group, the time to achieve the TOF of 0 was greater in the experimental group (123 vs 96 seconds, p = 0.030). On the other hand, pharmacological reversal with sugammadex was observed with the same frequency in both groups. Conclusions: in this trial, we concluded that the time to reach TOF of 0 was longer for the priming group. However, it is important to mention that the time needed for TOF of 0 with doses of 0.6 mg/kg without priming reaches up to four minutes; while in the study we observed that when priming with a dose of 0.6 mg/kg it can be reduced to 123 seconds.

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