medigraphic.com
ISSN 1561-3119 (Electronic)

2022, Number 1

<< Back Next >>

Rev Cubana Pediatr 2022; 94 (1)

Coqueluchoid syndrome and whoesteer

Vega-Mendoza DL, Dotres-Martínez C, Toraño-Peraza G, Valdés-Ramírez O, Mondeja-Rodríguez BA

Language: Spanish
References: 24
Page: 1-14
PDF size: 857.72 Kb.


ABSTRACT

Introduction: Coqueluchoid syndrome is a frequent cause of admission and Bordetella pertussis is not always ruled out as its origin.
Objective: Identify the infectious etiology in children admitted with coqueluchoid/coqueluche syndrome and its relationship with vaccination status.
Methods: A descriptive, cross-sectional study was conducted in 120 children up to 10 years of age diagnosed with coqueluchoid syndrome admitted to the Pulmonology Service of "Juan Manuel Márquez" Children's Hospital between January 2010 and September 2012. Age, sex, evolution, polymerase chain reaction results and culture for viruses, bacteria and mycoplasmas were evaluated in samples obtained at admission, processed at the Institute of Tropical Medicine ; in addition to the compliance with anti-pertussis vaccination. Qualitative variables were described by absolute frequencies and percentages; to evaluate the ratio of whooping cough and non-compliance with vaccination, the Ji square test was used with a significance level of p≤ 0.05.
Results: Children under one year of age (69.2%) and female sex (55%) predominated. Bordetella pertussis was isolated in 71 cases (59.2%); it was more frequent in children under 6 months (59.7%) and in children with incomplete vaccination (80%), but the difference with non-pertussis cases was not significant (p= 0.214). There was co-infection with viruses and mycoplasmas (54-76%). Viral etiology predominated in the remaining 49; rhinovirus was the most represented overall. A newborn died with B. pertussis pneumonia.
Conclusions: In the face of a coqueluchoid syndrome we must always keep in mind the possibility of whooping cough, especially in young children with incomplete vaccination.


REFERENCES

  1. Dotres-Martínez C, Vega-Mendoza D, Toraño-Peraza G, Álvarez-Carmenate M, Broche-Morera A. Síndrome coqueluchoide y tos ferina. Rev. cuban. med. gen. integr. 2012 [acceso 19/02/2021];28(4):725-34. Disponible en: https://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21252012000400015&lng=es

  2. Cevallos-Bustamante B, Hernán A, Campos-Tejada VM. Características clínico epidemiológica del síndrome coqueluchoide en pacientes hospitalizados en el servicio de pediatría en el Hospital Regional Docente de Cajamarca, en el periodo 2018. Cajamarca: Universidad Nacional, Facultad de Medicina Humana, Escuela Académico Profesional de Medicina Humana; 2019 [acceso 19/02/2021] Disponible en: https://alicia.concytec.gob.pe/vufind/Record/RUNC_92d38f29a458cae03eb7edbd4b15f4fb

  3. Long SS. Pertussis (Bordetellapertussis and Bordetellaparapertussis). En: Kliegman RM, Stanton B, StGeme JW, Schor NF,editors. Nelson. Tratado de Pediatría, 20a ed. España: Elsevier;2016. p.1377-82.

  4. Bottero D, Gabrielli M, Aispuro PM, Regidor V, Hozbor D. Pertussis, historia, hechos y situación actual. Acta Bioquímica Clínica Latinoamericana 2019 [acceso11/08/2021];53(3):343-52. Disponible en: https://www.redalyc.org/journal/535/53562084014/html/

  5. O. P. D. Salud. Manual de procedimientos para la atención del Síndrome coqueluchoide/tos ferina. Tlaxcala: TLX Construir juntos. México: Gobierno de Estado de Tlaxcala; 2017 [acceso 15/08/2021] Disponible en: https://www.saludtlax.gob.mx/documentos/organizacion/ManualesProcedimientos/6_MANUAL%20DE%20PROCEDIMIENTOS_ATENCION_DEL_SINDROME_COQUELUCHOIDE.pdf

  6. Pérez Zárate, NP, Rodríguez-Borroel M, Jaime-Guzmán JJ, Reyes- Estrada CA, Gutiérrez-Hernández R. Tendencia epidemiológica de pacientes pediátricos zacatecanos con síndrome coqueluchoide positiva para tosferina. IBN SINA. 2017 [acceso19/02/2021];6(2). Disponible en: https://revistas.uaz.edu.mx/index.php/ibnsina/article/view/28

  7. Grande-Tejada AM. Actualización en tosferina. Rev Pediatr Aten Primaria. 2016 [acceso 15/08/2021];18(supl.25): Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1139-76322016000500007

  8. World Health Organization. Pertussis vaccines: WHO position paper August 2015. Vaccine. 2016;34(12):1423-5. DOI: https://doi.org/10.1016/j.vaccine.2015.10.136

  9. Yeung KHT, Duclos P, Nelson EAS, Hutubessy RCW. An update of the global burden of pertussis in children younger than 5 years: a modelling study. Lancet Infect Dis 2017;17:974-80. DOI: https://doi.org/10.1016/S1473-3099(17)30390-0

  10. Masseria C, Martin CK, Krishnarajah G, Becker LK, Buikema A, Tan TQ. Incidence and burden of pertussisamonginfantslessthan 1 year of age. Pediatr Infect Dis J 2017;36(3):e54*61. DOI: https://doi.org/10.1097/INF.0000000000001440

  11. Gopal DP, Barber J, Toeg D. Coqueluche, tos convulsa, pertussis.. BMJ 2019 [acceso 26/01/ 2021];364-401. DOI: https://doi.org/10.1136/bmj.401

  12. Mir-Cros A, Codina G, Martín-Gómez MT, Fàbrega A, Martínez X, Jané M, et al. Emergence of Bordetella holmesii as a causative agent of Whooping Cough, Barcelona, Spain. Emerg Infect Dis 2017;23(11):1856-9 DOI: https://doi.org/10.3201/eid2311.170960

  13. Daniels HL, Sabella C. Bordetella pertussis (Pertussis). Pediatr Review. 2018;39(5): 247-57. DOI: 10.1542/pir.2017-0229

  14. Mahecha-Valencia LM, Vizcaíno A, Cifuentes D, Cano T, Ariza Y, González-Ángel LA, et al. Lo que debemos saber los terapeutas respiratorios. Bogotá: Fundación Universitaria del Área Andina; 2019 [acceso 26/01/2021]. Disponible en: https://digitk.areandina.edu.co/bitstream/handle/areandina/3498/2019_11_12_TerapeutasRespiratorios_v2.pdf?sequence=1

  15. Centers forDisease Control and Prevention. Epidemiology and Prevention of Vaccine-Preventable Diseases. 13 ed. Supplement. Washington D. C. Public Health Foundation: CDC; 2017 [acceso 26/01/2021]. Disponible en: https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/supplement.pdf

  16. Liang Y, Salim AM, Wu W, Kilgore PE. Chao Yuanfang: imperial physician of the Sui dynasty and a nearly pertussis observer? Open Forum Infect Dis. 2016;3:ofw017. DOI: https://doi.org/10.1097/INF.0000000000001440

  17. Siriyakorn N, Leethong P, Tantawichien T. Adult pertussisis unrecognized public health problem in Thailand. BMC Infect Dis. 2016;16:25. DOI: https://doi.org/10.1016/j.jtho.2020.04.024

  18. Galindo-Sardiñas MA. Inmunizaciones. En: Prieto D, ed. Pediatría. Diagnóstico y tratamiento. 3ra ed. La Habana: Editorial Ciencias Médicas; 2016. p. 90-92.

  19. Torres RSLA, Santos TZ, Torres RAA, Pereira VVG, Fávero LAF, Filho ORM, et al. Resurgence of pertussis at the age of vaccination: clinical, epidemiological, and molecular aspects. J Pediatr (Rio J). 2015;91(4):333-8 DOI: http://dx.doi.org/10.1016/j.jped.2014.09.004

  20. Fernández-Cano MI, Armadans-Gil L, Martínez-Gómez X, Campins-Martí M. Incidence of whooping cough in Spain (1997-2010): an under reported disease. Eur J Pediatr. 2014;173:721-6. DOI: 10.1007/s00431-013-2228-8

  21. Astudilla M, Estrada VE, de Soto MF, Ángela L. Infección por Bordetella pertussis en contactos domiciliarios de casos de tosferina en el suroriente de la ciudad de Cali, Colombia 2006-2007. Colomb Med. 2011 [acceso 26/01/2021];42(2). Disponible en: https://www.scielo.org.co/scielo.php?pid=S1657-95342011000200007&script=sci_abstract

  22. Trevizan S, Duarte SE. Epidemiological profile of pertussis in Rio Grande do Sul State, Brazil: a study of the correlation between incidence and vaccine coverage. Cad Saúde Publica. 2008 [acceso 27/07/2021];24(1). Disponible en: https://www.scielo.br/scielo.php?pid=S0102-311X 2008000100009&script=sci_arttext&tlng=pt

  23. Ministerio de Salud Pública de Cuba. Dirección Nacional de Registros Médicos y Estadísticas de Salud. Anuarios Estadísticos de Salud. La Habana: Minsap; 2013 [acceso 20/02/2021]. Disponible en: http://www.sld.cu/sitios/dne/

  24. Montes de Oca-Melián A. Tos ferina. Pediatr Integ. 2018 [acceso 20/02/2021];12(6): 254-63 Disponible en: https://www.pediatriaintegral.es/publicacion-2018-09/tosferina/




2020     |     www.medigraphic.com