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ISSN 1561-3119 (Electronic)

2022, Number 1

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Rev Cubana Pediatr 2022; 94 (1)

Clinical manifestations of factor XII deficiency in an infant

Patarroyo VDA, Martínez EN

Language: Spanish
References: 9
Page: 1-7
PDF size: 309.82 Kb.


ABSTRACT

Introduction: Factor XII or Hageman factor belongs to the contact system as it is the initiator of the intrinsic coagulation pathway. Low concentrations of this factor are associated with prolonged activated partial thromboplastin time, however, hemorrhagic manifestations do not occur as occurs in the deficiency of other factors.
Objective: Describe the clinical manifestations of an infant diagnosed with coagulation factor XII deficiency.
Case presentation: A 10-month-old infant who had spontaneous onset of ecchymosis and a factor XII deficiency was diagnosed.
Conclusions: Although not common, factor XII deficiency may be associated with hemorrhagic manifestations such as ecchymosis, as described in the present case.


REFERENCES

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