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2023, Number 7

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Med Crit 2023; 37 (7)

Association between the level of fragility prior to admission to the Intensive Care Unit with mortality at hospital discharge in critically ill patients

García MC, Muralla SLI, Cerón DUW
Full text How to cite this article 10.35366/114855

DOI

DOI: 10.35366/114855
URL: https://dx.doi.org/10.35366/114855

Language: Spanish
References: 8
Page: 547-551
PDF size: 207.32 Kb.


Key words:

clinical frailty scale, CFS, mortality, ICU, intensive care unit, frailty, risk prediction.

ABSTRACT

Introduction: frailty prior to admission to critical care units, measured with the clinical frailty scale (CFS), is associated with mortality. Objectives: to determine the association between the CFS score prior to admission to the Intensive Care Unit (ICU) and mortality at hospital discharge in critically ill patients in a private tertiary hospital. Material and methods: an observational, longitudinal, prospective study was conducted. It included all patients admitted to the ICU from March 1 to June 30, 2023. Results: 116 patients with a mean age of 64.2 ± 17.8 years, 45.7% were women. Overall mortality was 18.1%, and it was higher in patients with CFS score ≥ 4 (p = 0.003). The univariate analysis found that the patients who died had as associated factors the SAPS 3 score (p < 0.001), SOFA (p < 0.001), hours of mechanical ventilation (p = 0.004) and CFS score (p = 0.003). In the multivariate analysis, through logistic regression, it was found that the days of hospital stay (p = 0.001), the SOFA score (p < 0.001), the hours of mechanical ventilation (p = 0.015) and the CFS score (p = 0.003) were variables that were independently associated with mortality. Conclusions: CFS is a variable that is independently associated with mortality at hospital discharge and can be used for its convenience to estimate the impact of the condition prior to admission to the ICU on the prognosis of critically ill patients.


REFERENCES

  1. McDermid RC, Stelfox HT, Bagshaw SM. Frailty in the critically ill: a novel concept. Crit Care. 2011;15(1):301. doi: 10.1186/cc9297.

  2. De Biasio JC, Mittel AM, Mueller AL, Ferrante LE, Kim DH, Shaefi S. Frailty in critical care medicine: a review. Anesth Analg. 2020;130(6):1462-1473. doi: 10.1213/ANE.0000000000004665.

  3. Muscedere J, Waters B, Varambally A, Bagshaw SM, Boyd JG, Maslove D, et al. The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis. Intensive Care Med. 2017;43(8):1105-1122. doi: 10.1007/s00134-017-4867-0.

  4. Pérez-Zepeda MU, Rodríguez MA, Wong R. Envejecimiento en México: fragilidad. Boletín Informativo del ENASEM; 2020.

  5. Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005;173(5):489-495. doi: 10.1503/cmaj.050051.

  6. Jung C, Guidet B, Flaatten H; VIP study group. Frailty in intensive care medicine must be measured, interpreted and taken into account! Intensive Care Med. 2023;49(1):87-90. doi: 10.1007/s00134-022-06887-8.

  7. Darvall JN, Bellomo R, Paul E, Bailey M, Young PJ, Reid A, et al. Routine frailty screening in critical illness: a population-based cohort study in Australia and New Zealand. Chest. 2021;160(4):1292-1303. doi: 10.1016/j.chest.2021.05.049.

  8. Pasin L, Boraso S, Golino G, Fakhr BS, Tiberio I, Trevisan C. The impact of frailty on mortality in older patients admitted to an Intensive Care Unit. Med Intensiva (Engl Ed). 2020:S0210-5691(20)30191-1. doi: 10.1016/j.medin.2020.05.019.




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Med Crit. 2023;37