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2024, Number 2

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Rev Mex Anest 2024; 47 (2)

Risk factors associated with abstinence syndrome in newborns with sedoanalgesia

Moreno-Saldaña JL, Gómez-Rodríguez G, Rodríguez-Mejía EJ, León-Verdín G, Gómez-Velázquez JJ

Language: Spanish
References: 14
Page: 86-90
PDF size: 250.54 Kb.


ABSTRACT

Introduction: opiates and benzodiazepines are the ones that most frequently produce withdrawal syndrome. Objective: know the risk factors associated with abstinence syndrome in patients whit sedoanalgesia. Material and methods: prospective, longitudinal, analytical; newborns received sedoanalgesia with fentanyl and midazolam for more than 24 hours. The clinical-demographic association with abstinence syndrome was analyzed using the Finnegan scale. Test t-Student, Mann-Whitney U and Mann-Whitney, χ2 for differences in different variables, logistic regression the independent variables associated with abstinence syndrome, alpha level < 0.05, SPSS v.23.0 program. Results: 84 patients, 56% male, predominated means: weeks of gestation 35 ± 3.8, weight 2,350 ± 866 g and cesarean 65.5%. To the Finnegan scale 7.1% file abstinence syndrome which 66.7% was mild and 33.3% moderate; the association between the presence of abstinence syndrome is found: cesarean, maternal age of 30 years, male, first or second gestation, 38 weeks gestation (p ≤ 0.01), weighing greater than 2,700 g, diagnosed with post-surgical admission and mechanical ventilation. Conclusion: there is a relationship between clinical demographic variables in newborn patients receiving sedoanalgesia and the presentation of with abstinence syndrome; however further studies are required to establish and adopt preventive measures.


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