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2024, Number 1

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Dermatología Cosmética, Médica y Quirúrgica 2024; 22 (1)

Resolution of caha nodules with synergistic STS and cannula subcision

Rullan P, Ly K, C Lee K
Full text How to cite this article

Language: English
References: 6
Page: 91-94
PDF size: 192.54 Kb.


Key words:

calcium hydroxylapatite nodules, caha nodules, sodium thiosulfate, triamcinolone, subcision.

ABSTRACT

Background: calcium hydroxylapatite (CAHA) is frequently used for cosmetic enhancement of facial, neck, and other body areas. An undesireable side effect of caha dermal filler injections are nodules, which can been seen and felt underneath the skin. Current treatments for resolution of CAHA nodules are controversial. Publications have suggesting a role for saline, hyaluronic acid, and sodium thiosulfate in resolving these nodules.
Material and methods: we present two cases of patients with caha-induced nodules that were resolved with a combination of sodium thiosulfate, or in some cases, additional triamcinolone injection, and subcision.
Results: two patients, ages 50- and 49-years old, presented with caha-induced nodules on the neck and face, respectively. The nodules were treated with a combination technique of a 1:1 dilution of 1% lidocaine and sodium thiosulfate (mixed 1:1), triamcinolone, and subcision. Up to three treatments using this technique resulted in resolution of visible caha nodules.
Conclusions: dermal CAHA nodules can be effectively treated with combination treatments consisting of 1% lidocaine and sodium thiosulfate, triamcinolone, and subcision.


REFERENCES

  1. Danysz W, Nowag B, Hengl T, Kreymerman P et al., Can sodiumthiosulfate act as a reversal agent for calcium hydroxylapatitefiller? Results of a Preclinical Study, Clin Cosmet Investig Dermatol 2020; 13:1059-73. Published 2020 Dec 31. doi: 10.2147/CCID.S271760.

  2. Robinson DM, In vitro analysis of the degradation of calcium hydroxylapatitedermal filler: a proof-of-concept study, Dermatol Surg2018; 44 Suppl 1:S5-9. doi: 10.1097/DSS. 0000000000001683.

  3. Kreymerman PA and Miller W, Sodium thiosulfate injection dissolvescalcium hydroxylapatite particles: an animal study, J AmAssoc Dermatol 2018; 79(3):S1.

  4. Yankova M, Pavicic T, Frank K, Beleznay K et al., Intraarterial degradationof calcium hydroxylapatite using sodium thiosulfate: anin vitro and cadaveric study, Aesthet Surg J 2021; 41(5):NP226-36. doi:10.1093/asj/sjaa350.

  5. Aksenenko I, Gerasimenko M, Polunina V and Evstigneeva I, Amethod for treating complications developed following countourcorrection with calcium hydroxylaptite-based filler, J ClinAesthet Dermatol 2022; 15(3):38-43.

  6. Rullan PP and Lee KC, Successful management of extremepain from delayed embolization after hyaluronic acid filler injection,jaad Case Rep 2019; 5(7):569-71.




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Dermatología Cosmética, Médica y Quirúrgica. 2024;22