2020, Number 1
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Cir Card Mex 2020; 5 (1)
Professor John Barlow - The Legend
Antunes MJ
Language: English
References: 14
Page: 1-5
PDF size: 335.33 Kb.
Text Extraction
BARLOW DISEASE OR SYNDROME ? Prof. John Barlow (Fig. 1) gained his place amongst
the giants of Cardiology because of his discovery of
the mechanism of the mitral valve failure that became
known as the Barlow Syndrome. There is great confusion
amongst the cardiological fraternity about syndrome,
disease and prolapse. Although Prof. Barlow was one of the
first to characterize mitral valve prolapse, his real contribution
was in deciphering “The significance of late systolic
murmurs and mid-late systolic clicks”. He attributed these
sounds to the mitral valve mechanism. Prior to that, they
were thought to be of extra-cardiac origin, including pericardial
adhesions.
REFERENCES
Barlow JB, Pocock WA. The significance of late systolic murmurs and mid-latesystolic clicks. Md State Med J. 1963;12:76-7
Barlow JB, Pocock WA, Marchand P, Denny M. The significance of late systolicmurmurs. Am. Heart J 1963;66:443-52
Barlow JB, Bosman. "Aneurysmal protrusion of the posterior leaflet of themitral valve. An auscultatory-electrocardiographic syndrome". Am. Heart J1966;71:166–78
Barlow, JB; Bosman CK; Pocock WA; Marchand P. Late Systolic Murmurs andNon-ejection ("Mid-Late") Systolic Clicks. An Analysis of 90 Patients". Br HeartJ,1968;30: 203–18
Barlow JB. Conjoint clinic on the clinical significance of late systolic murmursand non-ejection systolic clicks. J Chron Dis 1965;18:665
Barlow JB, Pocock WA. Mitral valve prolapse, the specific billowing mitral leafletsyndrome, or an insignificant non-ejection systolic click. Am Heart J 1979;97:277-85
Cohen M, Pocock WA, Lakier JB, McLaren MJ, Lachman AS, Barlow JB. Fouryearfollow-up of black schoolchildren with non-ejection systolic clicks and mitralsystolic murmurs. Am Heart J. 1978;95:697-701
Jankelow D. A tribute to Professor John Brereton Barlow. Adler Museum Bulletin.2012;38: 18–25.
Barlow JB, Shillingford J. The use of amyl nitrite in differentiating mitral andaortic systolic murmurs. Brit. Heart J 1958;20:162-6
Barlow JB, Pocock WA. The significance of aortic ejection systolic murmurs. AmHeart J. 1962 Aug;64:149-58
Antunes MJ, Kinsley RH. Mitral valve annuloplasty: results in an underdevelopedpopulation. Thorax. 1983;38:730-6
Antunes MJ. Mitral Valve Repair. RS Schulz, Dusseldorf, 1989
Barlow JB. Perspectives on the Mitral Valve. FA Davis Company, Philadelphia,1986
Antunes MJ, Barlow JB. Management of tricuspid valve regurgitation. Heart.2007;93:271-6.