Santamaría-Arza C, Perea-Martínez A, Reyes-Hernández KL, López-Navarrete G, Reyes-Gómez U, Virgen-Ortega C, Guerrero-Becerra M, Merlo-Palomera M, López-Cruz G, Hernández-García MA, Vargas-Mosso ME, Fraga-Pérez J

Language: Spanish
References: 12
Page: 146-151
PDF size: 207.62 Kb.

ABSTRACT

Obesity causes the individual to be in a state of greater immunological vulnerability against infectious processes, mainly due to a functional modification of leptin, this is an adipokine known as the most important regulator of hunger, by generating a satiety effect at the hypothalamic level. However, this adipokine has been studied and recognized for different systemic functions, one of which is its effect on regulating immune function. In a susceptibility sample matched for age, sex, race, and diabetes mellitus, the risk of urinary tract infection (UTI) increased by 45% in obese women, a result that was not consistent with men, in those who were not the association was found. In a finding of significant relevance, it can be presumed not only a higher risk of developing a urinary tract infection but also greater severity. It was found that, out of a total of 51,918 patients under 18 years of age with UTIs, 1,488 were obese and 50,430 were not. Among patients with UTI, compared to lean children, obese children showed a longer duration of fever and a higher frequency of incidence of hydronephrosis.

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