medigraphic.com

2022, Number 2

Next >>

Folia 2022; 16 (2)

Behaviour of squamous cell carcinoma in Pinar del Río province

Giniebra MGM, Rivera RR, Gorrín DY

Language: Spanish
References: 18
Page:
PDF size: 428.35 Kb.


ABSTRACT

Introduction: Squamous cell carcinoma is a malignant tumor derived from epidermal kertinocytes, with metastatic potential. Its incidence is increasing both globally and in Cuba.
Objective: To characterize the clinical and epidemiological behavior of patients with squamous cell carcinoma.
Methods: A descriptive, longitudinal and retrospective study was carried out in patients with clinical and histological diagnosis of squamous cell carcinoma in the hospitals of León Cuervo Rubio and Abel Santamaría Cuadrado áreas in the province of Pinar del Río, during the period from January 2019 to December 2020. The universe consisted of 1817 patients, and the sample of 453 patients. The variables age, sex, skin color, clinical forms location and degee of tumor differentiation were studied. Biopsy reports and cancer reports were used to obtain the information.
Results: 45.91% of patients were over 60 years old, 60.70% were male and 417 had white skin. The most frequent clinical form was ulceration with 109 cases, the main tumor location was in the head and neck with 108 patients and 57.17% had a well-differentiated tumor.
Conclusions: No differences were found in terms of epidemiology, clinical data, and histology, compared to what was reported in the literature.


REFERENCES

  1. López Cruz ZC. Incidencia de carcinoma basocelular y epidermoide. Dermatología Rev Mex. 2017 [acceso 12/03/2020];51(4):149-53. Disponible en: http://www.medigraphic.com/pdf/derrevmex/rmd2007/rmd074c.pdf

  2. Uribe-Bojanini E, Londoño García AM, Jiménez Calfat G, Sanabria Quiroga AE, Mejía Montoya ME. Carcinoma espinocelular de piel de alto riesgo: definición, diagnóstico y manejo. Med Cutan Iber Lat Am. 2017 [acceso 18/05/2020];45(1):8-13. Disponible en: https://www.medigraphic.com/pdfs/cutanea/mc-2017/mc171b.pdf

  3. NCCN Clinical Practice Guidelines in Oncology. Basal cell skin cancer. Version 2. 2018. [acceso 01/07/2020]. Disponible en: https://www.nccn.org/professionals/physician_gls/f_guidelines.asp

  4. Sánchez G, Nova J. Factores de riesgo del carcinoma espinocelular, un estudio del Centro Nacional de Dermatología de Colombia. Actas Dermosifiliogr. 2013 [acceso 01/07/2020];104(8):672-8. Disponible en: https://www.sciencedirect.com/science/article/pii/S0001731013000604

  5. Thompson AK, Kelley B, Prokop L, Murad M, Baum C. Risk factors for cutaneous squamous cell carcinoma recurrence, metastasis and disease-specific death: a systemic review and meta-analysis. JAMA Dermatol. 2018 [acceso 01/07/2020];152(4):419-28. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26762219/

  6. Bishakjian CK, Olencki T, Aasi SZ, Alam M, Andersen JS, Berg D, et al. NCCN Guidelines Version 1. 2017. Panel Members Squamous Cell Skin Cancer. Disponible en: https://es.scribd.com/doc/295173447/squamous-Cell-Skin-Cancer-NCCN-Guidelines

  7. Hernández-Zárate SI, Medina-Bojórquez A, López-Tello S, Alcalá-Pérez D. Epidemiología del cáncer de piel en pacientes de la Clínica de Dermato-oncología del Centro Dermatológico Dr. Ladislao de la Pascua. Estudio retrospectivo de los últimos ocho años. Dermatol Rev Mex. 2018 [acceso 01/06/2020];56(1):30-7. Disponible en: http://www.medigraphic.com/pdfs/derrevmex/rmd-2012/rmd121e.pdf

  8. Güémez-Granie MF, Plascencia-Gómez A, Graniel-Lavadore MJ, Dzul-Rosado K. Epidemiología del cáncer de piel en el Centro Dermatológico de Yucatán. Dermatol Rev Mex. 2015 [acceso 01/07/2020];59:9-18. Disponible en: https://www.medigraphic.com/pdfs/derrevmex/rmd-2015/rmd151c.pdf

  9. Telich Tarriba JE, Monter Plata A, Victor Baldin A, Apellaniz Campo A. Diagnóstico y tratamiento de los tumores malignos de piel. Acta Med Grupo Angeles. 2017 [acceso 01/07/2020];15(2):8-13. Disponible en: http://www.scielo.org.mx/pdf/amga/v15n2/1870-7203-amga-15-02-00154.pdf

  10. Gandhi SA, Kampp J. Skin cancer epidemiology, detection and management. Med Clin North Am. 2015 [acceso 10/07/2020];99(6):1323-35. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26476255/

  11. Krediet JT, Beyer M, Lenz K, Ulrich C, Lange-Asschenfeldt B, Stockfleth E, et al. Sentinel lymph node biopsy and risk factors for predicting metastasis in cutaneous squamous cell carcinoma. Br J Dermatol. 2015 [acceso 01/07/2020];172(4):1029-36. Disponible en: https://pubmed.ncbi.nlm.nih.gov/25362868/

  12. Metterle L, Nelson C, Patel N. Intralesional 5-fluorouracil (FU) as a treatment for nonmelanoma skin cancer (NMSC): A review. J Am Acad Dermatol. 2016 [acceso 15/07/2020];74(3):552-7. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0190962215022458#:~:text=Intralesional205fluorouracil

  13. Kallini J, Hamed N, Khachemoune A. Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends. Int J Dermatol. 2017 [acceso 15/07/2020];54(2):130-40. Disponible en: https://onlinelibrary.wiley.com/doi/abs/10.1111/ijd.12553

  14. Domínguez-Cherit J, Rodríguez-Gutiérrez G, Narváez Rosales V, Toussaint Caire S, Fonte Avalos V. Características del carcinoma epidermoide cutáneo y riesgo para el desarrollo de recidivas con cirugía convencional y cirugía con transoperatorio tardío. Cir Cir. 2017 [acceso 15/07/2020];85(6):499-503. Disponible en: https://www.sciencedirect.com/science/article/pii/S0009741116301347

  15. Muranushi C, Olsen CM, Pandeya N, Green AC. Aspirin and nonsteroidal anti-inflammatory drugs can prevent cutaneous squamous cell carcinoma: a systemic review and meta-analysis. J Invest Dermatol. 2015 [acceso 23/07/2020];135(4):975-83. Disponible en: https://www.sciencedirect.com/science/article/pii/S0022202X15371852

  16. Schawaederle M, Elkin SK, Tomson BN. Carter JL, Kurzrock R. Squamousness: next generation sequencing reveals shared molecular festures across squamous tumor types. Cell cycle. 2016 [acceso 12/07/2020];1:1-7. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26030731/

  17. Rogers HW, Weinstock MA, Feldman SR, Coldiron BM. Incidence estimate of nonmelanoma skin cancer in the U.S. population. Jama Dermatol. 2016 [acceso 23/07/2020];151(10):1081-6. Disponible en: https://pubmed.ncbi.nlm.nih.gov/25928283/

  18. Li L, Li F, Xia Y, Yang X, Lv Q, Fang F, et al. UVB induces cutaneous squamous cell carcinoma progression by de novo ID4 methylation via methylation regulating enzymes. EBioMedicine. 2020 [acceso 28/07/2020];57:e102835. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32574963/




2020     |     www.medigraphic.com