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ISSN 2520-9078 (Electronic)

2022, Number 2

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Revista de Ciencias Médicas de la Habana 2022; 29 (2)

Clinical, radiological and laboratorial characteristics in patients with COVID-19 treated by Jusvinza

Acosta PYD, García MRD, Domínguez MA, Felipe FIC

Language: Spanish
References: 19
Page: 218-228
PDF size: 409.21 Kb.


ABSTRACT

Introduction: The treatment with monoclonal antibodies in the infection by SARS-CoV-2 is controversial, some protocols recommend it for patients with an acute disease or in a critical status.
Objective: To characterize infected patients by COVID-19 admitted to the Intensive Care Unit under treatment with Jusvinza.
Methods: An observational, descriptive cross-sectional and prospective study was carried out with seven patients with acute disease by COVID-19, admitted to the Intensive Care Unit, in the Bolivarian Republic of Venezuela, from March to July, 2020. The cases were characterized according to the following variables: age, sex, comorbidities, associated symptoms; extension of the radiological lesions, clinical laboratory values; respiratory distress severity, time of ventilator support and hospital stay, complications and mortality.
Results: The male sex and ages from 55 to 74 years old prevailed. Asthma was the most frequent comorbidity. The most frequent symptoms were cough, fever and asthenia. The diffuse bilateral infiltrate prevailed in the chest X-rays and neutrophilia with lymphopenia. According to the relation PO2/FIO2, moderate distress prevailed. Time of ventilator support for patients oscillated between 5 and 10 days, and hospital stay was more than 14 days. The most observed complication was pneumonia associated to ventilation and no deceased was registered.
Conclusions: In patients with SARS-CoV-2 and acute diseases treated by Jusvinza, an average time of ventilator support less than seven days is observed and no deceased is registered.


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