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2024, Number 2

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Rev Mex Traspl 2024; 13 (2)

Management of hypotension during the maintenance of the multi-organ donor and its relationship with the viability of cardiac procurement. A literature review

Ovalle-Valencia MF, Barrientos-Núñez ME

Language: Spanish
References: 28
Page: 85-91
PDF size: 248.16 Kb.


ABSTRACT

The procurement of organs and tissues for transplantation in Mexico is carried out thanks to patients who develop brain death and decide to donate. Brain death entails a complex process of pathophysiological changes in the person who suffers it, leading to a deregulation of the organism and complications in the stability of the donor. The most common condition is hypotension, caused by a deregulation of the nervous system, hormonal failures, hypovolemia and diabetes insipidus, among other reasons. It is necessary to properly manage the multi-organ donor to maintain optimal hemodynamic parameters and achieve the procurement of the appropriate organs and tissues. This management should be evaluated and carried out according to the characteristics of the donor and their conditions. There are several types of treatment for hypotension, including therapy with vasopressors, inotropes, corticosteroids and hormones. However, most pharmacological treatments have shown significant risks regarding cardiac viability for organ procurement. It is necessary to carry out more comprehensive studies to develop a more standardized therapy at the national and international levels, as well as to evaluate the impact on each organ secondary to each of the treatments.


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