Alcocer SM, Santiago BMJ, Ibarra TDM, Zepeda TJM, Tarango MVM, Sánchez MAP

Language: Spanish
References: 6
Page: 75-77
PDF size: 364.86 Kb.

ABSTRACT

Trichosporon asahii is considered the causative agent of trichosporonosis. Typically is associated with surface-level infections, but has the capacity to disseminate, leading to fungemia, often proving fatal. Individuals with immunocompromise or hematological malignancies face heightened susceptibility to this infection. We show the clinical case of 52-year-old woman diagnosed with systemic lupus erythematosus and chronic kidney disease who required immunosuppressant therapy and mechanical ventilation. She developed a dermatosis localized in the left hypochondrium, with erythematous-violet macules and papules featuring ulcerated-necrotic areas. Trichosporon asahii presence was confirmed, yet despite antifungal intervention, she progressed to refractory septic shock. Trichosporonosis represents a lethal fungemia, should be considerated in immunocompromised patients displaying fever, multiple organ failure, and a non-responsive dermatosis, with necrotic ulcers. While the optimal treatment remains undetermined, contemplating the usage of voriconazole, posaconazole, or ravuconazole is advised.

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