medigraphic.com
ISSN 1028-4796 (Print)

2022, Number 2

<< Back

Rev Cubana Plant Med 2022; 27 (2)

Pharmacological studies on Foeniculum vulgare Mill (fennel) and its concordance with traditional uses

Martínez TMC, Alfonso HA, Pérez CN, Díaz MI

Language: Spanish
References: 28
Page:
PDF size: 198.56 Kb.


ABSTRACT

Introduction: There is a renewed interest in medicinal plants, despite the large number of drugs and other therapeutic resources available. Among the plants, with wide use and publications, the Foeniculum vulgare Mill. (fennel) stands out, a fact that motivated us to carry out a review to try to collate the information available on the ethnomedical and pharmacological studies, both preclinical and clinical, found.
Objective: To relate the reports of preclinical and clinical pharmacological studies with the properties traditionally attributed to Foeniculum vulgare Mill.
Method: A bibliographic and documentary review was carried out, where articles published on the subject were collected, retrieved from PubMed, Scielo and academic Google electronic databases. The DeCs-MeSH descriptors were used: medicinal herbs, medicinal plants, Foeniculum, clinical study and preclinical study.
Results: About 63% of the articles were from the last 10 years, preclinical pharmacological studies and phytochemicals predominated; It is worth mentioning the little existence of studies carried out in Cuba.
Fennel has a wide range of traditional uses and pharmacological actions, among the most recurrent in the literature we can mention the effects: antispasmodic, anti-inflammatory, antibacterial, antifungal, antiviral, antinociceptive, antipyretic, anxiolytic, antihypertensive, cytoprotective, antitumor, antioxidant, diuretic , antihirsutism, estrogenic, expectorant, galactogenic, as well as hepatoprotective, hypoglycemic, lipid-lowering and nootropic effect.
Conclusions: In general, there is agreement between the traditional properties and the research carried out to validate these uses. The best studied effects are antimicrobial and antioxidant. Clinical studies and those conducted in Cuba are scarce.


REFERENCES

  1. Morales Pérez M, García Mesa M, Acosta de la Luz L, Vega Jiménez J, Céspedes Martínez I, Perdomo Delgado J. Una alternativa natural para el tratamiento de la COVID-19. Rev Cubana Plant Med. 2020 [acceso: 05/05/2022];25(1). Disponible en: http://www.revplantasmedicinales.sld.cu/index.php/pla/article/view/1024/430

  2. Blanco Hernández N, García Milián A. Necesidad de la formación por competencias para la prescripción racional de plantas medicinales. Rev Cubana Plant Med. 2019 [acceso: 05/05/2022];24(3). Disponible en: http://www.revplantasmedicinales.sld.cu/index.php/pla/article/view/914

  3. Renna M, Cocozza C, Gonnella M, Abdelrahman H, Santamaria P. Elemental characterization of wild edible plants from countryside and urban area. Food Chem. 2015;15(177):29-36. DOI: https://doi.org/10.1016/j.foodchem.2014.12.069

  4. Aguilar J, Taipe F. Comparación de aceite esencial de hinojo (Foeniculum vulgare Miller) extraído mediante métodos de arrastre a vapor y soxhlet. J Agro-Industry Sciences. 2020;20(3)[aprox. 4p.]. DOI: http://dx.doi.org/10.17268/JAIS.2020.005

  5. Renna M, Cocozza C, Gonnella M, Abdelrahman H, Santamaria P. Elemental characterization of wild edible plants from countryside and urban area. Food Chem. 2015;15(177):29-36. DOI: https://doi.org/10.1016/j.foodchem.2014.12.069

  6. González Ramírez M, Remirez D, Jacobo O. Antecedentes y situación reguladora de la medicina herbaria en Cuba. BLACPMA. 2007;6(4):118-24.

  7. Ceballos SJ, Perea MC. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas. 2014;13(1):47-68.

  8. Rahimi R, Ardekani M. Medicinal properties of Foeniculum vulgare Mill. in traditional Iranian medicine and modern phytotherapy. Rev Chin J Integr Med. 2013;19:73. DOI: https://doi.org/10.1007/s11655-013-1327-0

  9. Cardoso Moura A, Salla V, de Lima D, Zulian D. Levantamento etnobotânico de Maytenus ilicifolia Mart. ex Reissek em uma comunidade rural do Sudoeste do Paraná, Brasil. Rev Cubana Plant Med. 2018 [acceso: 05/05/2022];23(2). Disponible en: http://www.revplantasmedicinales.sld.cu/index.php/pla/article/view/485

  10. Pombo Ospina LM, Mejía Piñeros AL, Hernández Montaño JF, Iregui Piñeros ML, Ronderos Osorio J. Caracterización etnobotánica de las plantas medicinales empleadas en el tratamiento de las enfermedades cardiometabólicas, Villa de Leyva-Boyacá. Rev Cubana Plant Med. 2019 [acceso: 05/05/2022];24(2). Disponible en: http://www.revplantasmedicinales.sld.cu/index.php/pla/article/view/663

  11. Baca Guevara P, Delgado Ríos DM. Actividad antibacteriana del extracto etanólico de Foeniculum vulgare (hinojo) sobre Streptococcus mutans. [Tesis de grado] Lima: Universidad Privada de Huancayo “Franklin Roosevelt”; 2021 [acceso: 05/05/2022]. Disponible en: http://repositorio.uroosevelt.edu.pe/handle/ROOSEVELT/639

  12. Victoria Amador M. Repercusión del intercambio científico TRAMIL-Cuba en las investigaciones y difusión del uso de plantas medicinales. Rev Cubana Plant Med. 2015 [acceso: 05/05/2022];20(4). Disponible en: http://www.revplantasmedicinales.sld.cu/index.php/pla/article/view/365

  13. Mercado N, Danitz G. Efecto antiinflamatorio del extracto hidroalcohólico de las hojas de Foeniculum vulgare Miller en Rattus rattus var. Albinus. [Tesis de grado] Lima: Universidad Católica “Los Ángeles de Chimbote”; 2021 [acceso: 05/05/2022]. http://repositorio.uladech.edu.pe/handle/123456789/24352

  14. Alba Rosero C, Camacho R, Polanco M, Gómez S. Efecto relajante de las hojas de Ocimum basilicum y Foeniculum vulgare colombianas en íleon aislado de rata. Universitas Médica. 2009 [acceso: 05/05/2022];50(1). Disponible en: http://www.redalyc.org/articulo.oa?id=231018725008

  15. Castañeda Puelles J. Evaluar el efecto antifúngico in vitro del extracto etanólico de la semilla de Foeniculum vulgare Mill. “hinojo” contra cepa de Candida albicans ATCC 10804 in vitro. [Tesis de grado] Lima: Universidad Privada “Antenor Orrego”; 2016. Disponible en: https://hdl.handle.net/20.500.12759/2115

  16. Escobedo Vargas J, Sarimiento Paye EK, Torres Cruz FF, Huambo Alberto C, Villanueva Salas J. Effects of Foeniculum vulgare on the symptoms of students with Primary Dysmenorrhea. Rev Intern Salud Materno Fetal. 2020 [acceso: 05/05/2022]. Disponible en: http://ojs.revistamaternofetal.com/index.php/RISMF/article/view/146

  17. Ochoa Ayala KB. Efecto expectorante del extracto hidroalcohólico de las hojas de Foeniculum vulgare Mill. [Tesis de grado] Ayacucho: Universidad Nacional “San Cristóbal de Huaman”; 2018 [acceso: 05/05/2022]. Disponible en: http://repositorio.unsch.edu.pe/handle/UNSCH/3359

  18. Jang S, Yang D. The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats. PLoS One. 2018 Ap. 2018;13(4). DOI: https://doi,org/10.1371/journal.pone.0195624

  19. Zaidi S, Muhammad J, Shahryar S, Usmanghani K, Gilani A, Jafri W. Anti-inflammatory and cytoprotective effects of selected Pakistani medicinal plants in Helicobacter pylori-infected gastric epithelial cells. J Ethnopharmacol. 2012;141(1). DOI: https://doi,org/10.1016/j.jep.2012.03.001

  20. Lucana Saloma F. Efecto hipolipidémico del extracto hidroalcohólico de hinojo (Foeniculum vulgare M.) en ratas hipercolesterolémicas. [Tesis de grado] Universidad Católica de Santa María. Disponible en: http://tesis.ucsm.edu.pe/repositorio/handle/UCSM/8150

  21. Badgujar S, Patel V, Bandivdekar A. Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology. Biomed Res Int. 2014. DOI: https://doi.org/10.1155/2014/842674

  22. Araujo R, Souza I, Brondani D, Solidônio, E. Avaliação biológica de Foeniculum vulgare (Mill.) (Umbelliferae/Apiaceae). Rev Brasil Plant Med. 2015;15(2):257-63. DOI: https://doi.org/10.1590/S1516-05722013000200014

  23. Renna M, Cocozza C, Gonnella M, Abdelrahman H, Santamaria P. Elemental characterization of wild edible plants from countryside and urban area. Food Chem. 2015;15(177):29-36. DOI: https://doi.org/10.1016/j.foodchem.2014.12.069

  24. Kargozar R, Azizi H, Salari RA. Review of effective herbal medicines in controlling menopausal symptoms. Electron Physicia. 2017;9(11). DOI: https://doi.org/10.19082/5826

  25. Lee H, Lim H, Jun J. Fennel (Foeniculum vulgare) on management of menopausal symptoms: A protocol for systematic review of randomized controlled trials. Medicine (Baltimore). 2014;97(13). DOI: https://doi.org/10.1097/MD.0000000000010223

  26. Akha O, Bahar A, Zaeif Khorasani E, Kosaryan M, Saeedi M, Ebrahimzadeh M. The effect of fennel (Foeniculum vulgare) gel 3% in decreasing hair thickness in idiopathic mild to moderate hirsutism. A randomized placebo controlled clinical trial. Caspian J Intern Med. 2014;5(1). DOI: https://doi,org/10.19082/5826

  27. Lall N, Kishore N, Binneman B, Twilley D. Cytotoxicity of syringin and 4-methoxycinnamyl alcohol isolated from Foeniculum vulgare on selected human cell lines. Nat Prod Res. 2015;29(18). DOI: https://doi.org/10.1080/14786419.2014.999058

  28. Pombo Ospina LM, Mejía Piñeros AL, Hernández Montaño JF, Iregui Piñeros ML, Ronderos Osorio J. Caracterización etnobotánica de las plantas medicinales empleadas en el tratamiento de las enfermedades cardiometabólicas, Villa de Leyva-Boyacá. Rev Cubana Plant Med. 2019 [acceso: 05/05/2022];24(2). Disponible en: http://www.revplantasmedicinales.sld.cu/index.php/pla/article/view/663




2020     |     www.medigraphic.com