Astorga-González JA, Villalobos-Rodelo JJ, Chinchillas-Vega J, Beltrán-Ontiveros SA, Basurto-Flores JC, Urias-Barreras CM

Language: Spanish
References: 11
Page: 5-12
PDF size: 479.10 Kb.

ABSTRACT

Objective: To describe the demographic and clinico-pathological characteristics of salivary gland tumors diagnosed in the population of Sinaloa. Material and methods: This is a descriptive, retrospective, and cross-sectional study. All cases diagnosed as salivary gland tumors from January 2012 to December 2021 were included, from eight pathology services, including public and private laboratories of surgical pathology and oral pathology, in Culiacan, Sinaloa. Descriptive statistical analysis was performed, and the Chi-square test was used to analyze the relationship between variables, with SPSS v20. A p-value of ‹.05 was considered statistically significant. Results: A total of 147 cases were obtained. Of the 146 cases with recorded sex, 79 were women (54.1%) and 67 were men (45.9%), with a mean age of 57 ± 16 years, and an age range of 11 to 91 years. Sixteen histopathological subtypes were identified, with benign tumors being more frequent (n=103, 70.0%). Pleomorphic adenoma was the most common benign tumor (n=76, 51.7%) and mucoepidermoid carcinoma was the most common malignant tumor (n=15, 10.2%). The most frequent location was the parotid gland (n=85, 70.08%). Regarding the histological type of the tumor and the anatomical location, a statistically significant difference was found between the groups (p=0.00). Conclusions: Salivary gland tumors are generally benign, show a preference for the female gender, occur most frequently in the fourth to seventh decades of life, and are most located in the parotid gland. Pleomorphic adenoma and mucoepidermoid carcinoma are the most common benign and malignant tumors, respectively.

REFERENCES

1. Cunha JLS, Hernandez-Guerrero JC, de Al-meida OP, Soares CD, Mosqueda-Taylor A. Salivary Gland Tumors: A Retrospective Study of 164 Cases from a Single Private Practice Service in Mexico and Literature Review. Head and Neck Pathol 2021;15(2):523–31.

2. Rocha RP, Coca GRM, Fonseca PAJ. Ca-racterización epidemiológica y clínico-tera-péutica de las neoplasias malignas de glán-dulas salivales. Rev Cubana Cir 2019;58(2):1–14.

3. Guevara-Canales JO, Morales-Vadillo R, Guzmán-Arias G, Cava-Vergiú CE, Robello-Malatto JM, Guerra-Miller H, et al. Mucoepi-dermoid Carcinoma of the Salivary Glands: Survival and Prognostic Factors. J Maxillo-fac Oral Surg 2017;16(4):431–7.

4. Skálová A, Hyrcza MD, Leivo I. Update from the 5th Edition of the World Health Organi-zation Classification of Head and Neck Tu-mors: Salivary Glands. Head and Neck Pathol 2022;16(1):40–53.

5. González G, Linares V, Rivera M, Martínez M, Murrieta P, Sánchez G, et al. Frecuencia de tumores de glándulas salivales: Estudio retrospectivo en un centro de diagnóstico histopatológico universitario (1979-2012). Rev ADM 2013;70(5):239–45.

6. Mejía-Velázquez CP, Durán-Padilla MA, Gó-mez-Apo E, Quezada-Rivera D, Gaitán-Ce-peda LA. Tumors of the salivary gland in Me-xicans. A retrospective study of 360 cases. Med Oral Patol Oral Cir Bucal 2012;17(2):183–9.

7. Sotelo-Gavito J, Pérez-Montaño M, Alde-rete-Vázquez G, Capetillo-Hernández G, Grube-Pagola P. Tumores de glándulas sa-livales en Veracruz. Experiencia de dos ins-tituciones. Rev Med Inst Mex Seguro Soc 2018;56(2):154–7.

8. Campolo González A, Ramírez Skinner H, Vargas Díaz A, León Ramírez A, Goñi Espil-dora I, Solar González A. Epithelial tumors of salivary glands. Review of 286 pathology reports. Rev Med Chil 2018;146(10):1159–66.

9. Machío N, Kreilinger JJP, Blanco MB, Del Castillo Pardo De Vera JL, Contreras AM, García MB, et al. Malignant salivary gland tu-mors: a retrospective study of patients treated at La Paz hospital between 2008 and 2018. Rev Esp Cir Oral Maxilofac 2021;43(3):90–5.

10. Bauta-Milord R, Góngora-Gómez O, Eliza-beth Gómez-Vázquez Y. Clinical and patho-logical characterization of pleomorphic ade-noma of salivary glands Caracterización clí-nica y anatomopatológica del adenoma pleomórfico de glándulas salivales. Univ Méd Pinareña Mayo-Agosto [Internet]. 2021; Available from: www.revgaleno.sld.cu/in-dex.php/ump/article/view/519

11. Bussu F, Rigante M, Giglia V, Bastanza G, De orso E, Almadori G, et al. Clinical history, prognostic factors, and management of fa-cial nerve in malignant tumors of the parotid gland. Clin Exp Otorhinolaryngol 2014;7(2):126–32.