Amniotic fluid as the next generation of organ preservation solutions: “commentary on ´can amniotic fluid be an alternative organ preservation solution for cold renal storage´”

Gülname Findik Güvendi

2020, Number 2

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Rev Nefrol Dial Traspl 2020; 40 (2)

Amniotic fluid as the next generation of organ preservation solutions: “commentary on ´can amniotic fluid be an alternative organ preservation solution for cold renal storage´”

Güvendi GF

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Language: English
References: 6
Page: 183-184
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Dear Editor,

This letter is a comment on the paper by Büyük et al. entitled “Can amniotic fluid be an alternative organ preservation solution for cold renal storage?”.
In the mentioned paper amniotic fluid (AF) is suggested as an alternative material for cold storage in kidney transplantation.
When histopathological data at hematoxylin and eosin level are evaluated together with the results of immunohistochemical examination and TUNEL apoptosis evaluation, the results of the study may break a ground in terms of organ transplantation. Moreover another study that shows that AF can be effective as a preservative in terms of cold storage damage of the liver supports this idea. But yet there are still blind spots that needs to be clarified.

REFERENCES

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Büyük B, Demirci T, Adalı Y, Eroğlu HA. A new organpreservation solution for static cold storage of the liver.Amniotic fluid. Acta Cir Bras. 2019;34(4):e201900402.doi: 10.1590/s0102-865020190040000002.
Defoort P. Amniotic fluid volume. Elsevier, 2005.(International Congress Series). doi: 10.1016/j.ics.2004.12.033.
Xing-Long T, Ling W, Tan-Bing G, Yu-Guo Q, Yu-QiaoQ, Yan-Ping X. Potential function of amniotic fluidin fetal development-Novel insights by comparing thecomposition of human amniotic fluid with umbilicalcord and maternal serum at mid and late gestation.J Chin Med Assoc. 2009;72(7):368-73. doi: 10.1016/S1726-4901(09)70389-2.
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Nunes P, Mota A, Figueiredo A, Macário F, Rolo F,Dias V, et al. Efficacy of renal preservation: comparativestudy of Celsior and University of Wisconsinsolutions. Transplant Proc. 2007;39(8):2478-9. doi:10.1016/j.transproceed.2007.07.024.