medigraphic.com
SPANISH

Universidad Médica Pinareña

ISSN 1990-7990 (Electronic)
Revista Universitaria
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2022, Number 2

<< Back Next >>

Universidad Médica Pinareña 2022; 18 (2)

Main reasons that cancer is too difficult to treat

Adel-Dawood A
Full text How to cite this article

Language: English
References: 6
Page: 1-3
PDF size: 114.16 Kb.


Key words:

No keywords

Text Extraction

Mr. Editor:

Cancer is one of the largest global causes of death worldwide. In 2018 alone, around one in six deaths will be caused by cancer; 9,6 million people worldwide have been afflicted by cancer. While cancer has been detected since the 18th century, for this deadly disease we still do not have a standardized cure. The current approach to battling cancer care is on-going, pending major progress. The purpose of this study is to figure out why it is so difficult to treat cancer.
Treating cancer isn’t easy because it ultimately involves fighting your own body. Under the influence of the environment, genetics and unhealthy lifestyle, some cells break out of control. These cells start growing and quickly multiply while carrying a genetic mutation that allows them to divide uncontrollably. Eventually, they become tumors and start invading different tissues and organs. Cancer cells turn into hidden enemies within us. Newly formed cancer cells create an entire microenvironment around themselves. Cancer cells stimulate the formation of neovessels, which proliferate rapidly in most types of cancer. These vessels are then used to feed cancer cells and help them grow. This process of blood vessel formation is called angiogenesis. The new blood vessels support cancer cells by providing them with oxygen and nutrients.


REFERENCES

  1. Copland M, Jorgensen HG, Holyoake TL. Evolving molecular therapy for chronic myeloid leukaemia-are we on target? Hematology [Internet]. 2005 [cited 01/09/2020]; 10:349–359. Disponible en: https://www.tandfonline.com/doi/abs/10.1080/10245330500234195

  2. Fruhwirth GO, Kneilling M, de Vries IJM et al. The potential of in vivo imaging for optimization of molecular and cellular anti-cancer immunotherapies. Mol Imaging Biol[Internet]. 2018 [cited 01/09/2020]. Disponible en: https://doi.org/10.1007/s11307-018-1254-3.

  3. Pavlova NN, Thompson CB. The emerging hallmarks of cancer metabolism. Cell Metabolism [Internet]. 2016[cited 01/09/2020]; 23(1):27-47. Disponible en: https://doi:10.1016/j.cmet.2015.12.006.

  4. Kamphorst JJ, Nofal M, Commisso C, Hackett SR, Lu W, Grabocka E, Vander Heiden MG, Miller G, Drebin JA, Bar-Sagi D, et al. Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. Cancer Res[Internet]. 2015[cited 01/09/2020]; 75:544–553.Disponible en: https://doi.org/10.1158/0008-5472.CAN-14-2211

  5. Wang Z, Liu F, Fan N, Zhou C, Li D, Macvicar T, Dong Q, Bruns CJ, Zhao Y. Targeting Glutaminolysis: New Perspectives to Understand Cancer Development and Novel Strategies for Potential Target Therapies. Front Oncol[Internet]. 2020[cited 01/09/2020]; 10:589508.Disponible en: https://doi:10.3389/fonc.2020.589508.

  6. Catenacci DVT. Next-generation clinical trials: Novel strategies toaddress the challenge of tumormolecular heterogeneity. Mol Oncol[Internet].2015[cited 01/09/2020]; 9:967–996. Disponible en: https://doi:10.1016/j.molonc.2014.09.011.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Universidad Médica Pinareña. 2022;18