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2022, Number 2

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Correo Científico Médico 2022; 26 (2)

Morphometry of the ventricular myocardium from the eighth to twelfth week of prenatal development

Cruz SYC, Díaz RPA, Robles GLM, Barceló AA, Clemente RO
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Language: Spanish
References: 24
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Key words:

prenatal development, cardiac morphogenesis, morphometric method.

ABSTRACT

Introduction: The quantification of the development of the ventricular myocardium during the embryonic stage and the first weeks of the fetal period is essential for the establishment of the prenatal medicine precociously.
Objective: To describe morphometrically the development of the ventricular myocardium in its compacted portion from the eighth to twelfth week of prenatal development.
Methods: A series of cases were studied at the University of Medical Sciences of Holguín, Cuba, from May 2018 to May 2019. The universe included embryos and human fetuses from induced abortions with misoprostol at Vladimir Ilich Lenin Hospital of Holguín. The intentional sample was constituted by 22 specimens between 8 and 12 weeks that were processed with the inclusion method in paraffin, transversely sectioned in serial cuts and digitized using a stereostopic camera. The morphometric study was carried out using ImageJ professional system.
Results: Mean values for the thickness of the ventricular compact wall from the eighth to the twelfth week were: 0.182 mm; 0.183 mm; 0.233 mm; 252 mm and 270 mm for the right ventricle; 0.198 mm; 0.209 mm; 0.245 mm; 0.275 mm and 0.296 mm for the left ventricle and 0.307 mm; 0.357 mm; 371mm; 395 mm and 459 mm for the interventricular septum.
Conclusions: The thickness of the ventricular myocardium increased from the eighth to twelfth week with significant differences between each week, except for the right ventricular wall between the eighth and the ninth week.


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