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CorSalud (Revista de Enfermedades Cardiovasculares)

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2022, Number 2

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CorSalud 2022; 14 (2)

BRASH syndrome: A case report

Milian-Hernández EJ, Anzules-Guerra JB, Betancourt-Castellanos L, Colón-Núñez S, Zapata-Cevallos SI
Full text How to cite this article

Language: Spanish
References: 13
Page: 209-213
PDF size: 325.05 Kb.


Key words:

Bradycardia, Beta-blockers, Calcium channel blockers, Hyperkalemia, Chronic kidney disease, Shock.

ABSTRACT

BRASH syndrome results as a consequence of a chain of pathophysiological events that generally occurs in elderly patients, with underlying cardiac disease, treated with beta-blockers or calcium channel blockers, and who present hyperkalemia. This combination of events potentiates the adverse effects of these drugs, thus, bradycardia, hypoperfusion and shock may develop. We present the case of a 78-year-old male patient with a history of high blood pressure, diabetes mellitus and stage II chronic kidney disease, who was being treated with carvedilol and who attended the emergency department presenting the clinical features that character-ize the syndrome. Despite the implantation of a temporary transvenous pacemak-er, he died a few hours later. In this report is highlighted the importance of recog-nizing the factors that lead to the appearance of this syndrome, and the multimod-al treatment that these patients need as part of the therapeutic protocol.


REFERENCES

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CorSalud. 2022;14