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2024, Number 4

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Enf Infec Microbiol 2024; 44 (4)

Risk factors for oral colonization of Candida spp. in geriatric population

Morales ER, Hernández NM, Olivares LAM, Delgado SG, Valencia GC, Méndez SJL, Ponce RER, González PAA
Full text How to cite this article

Language: Spanish
References: 22
Page: 156-162
PDF size: 203.94 Kb.


Key words:

Candida, aged, diabetes mellitus, mouth mucosa, stomatitis.

ABSTRACT

Objective. To relate risk factors that favor oral colonization of different Candida species, on geriatric patients.
Material and methods. Observational, cross-sectional and analytical study in older adults with different underlying pathologies in a first-level clinic. An oral cavity sample was taken. Chi square of independence was used, in addition to a multivariate discriminant analysis and multiple logistic regression. SPSS v 26 Statistical Program.
Results. 172 older adults were included. In 36.6%, positive cultures were obtained for the different species of Candida. In the relationship between the presence of Candida and studied factors; for patients with diabetes, statistical significance was obtained with sex, use of mouthwash, stomatitis, smoking, polypharmacy, and use of ARA II. In patients with high blood pressure, with use of prostheses, edentulism and oral trauma. In the relation between risk factors and Candida species: for patients with diabetes mellitus, a relation was obtained with the use of mouthwash, diuretics, inhalers, and with intolerance to prostheses. In high blood pressure with the use of prostheses, allergy to prostheses, and with oral trauma.
Conclusions. In this study, relation between risk factors and colonization with different species of Candida in geriatric patients was established. Pre-existing comorbidities per se are not enough to favor colonization, synergy between these and the various risk factors specific to this age group makes the difference.


REFERENCES

  1. Calderone, R.A. y Braun, P.C., “Adherence and receptorrelationships of Candida albicans”, Microbiol Rev, 1991,55 (1): 1-20. doi: 10.1128/mr.55.1.1-20.1991.

  2. Moyes, D.L., Wilson, D., Richardson, J.P., Mogavero, S.,Tang, S.X., Wernecke, J. et al., “Candidalysin is a fungalpeptide toxin critical for mucosal infection”, Nature,2016, 532 (7597): 64-68. doi: 10.1038/nature17625.

  3. Delgado Azañero, W., Arrascue Dulanto, M. y LévanoLoayza, S., “Candidiasis hiperplásica crónica dela lengua: una lesión con cambios displásicos”, RevEstomatol Herediana, 2021, 31 (4): 303-310. Consultadoel 10 de abril de 2023. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1019-3552021000400303&lng=es2021; http://dx.doi.org/10.20453/reh.v31i4.4099.

  4. Cruz Quintana, S.M., Díaz Sjostrom, P., Arias Socarrás,D., Mazón Baldeón, G.M., “Microbiota de los ecosistemasde la cavidad bucal”, Rev Cubana Estomatol, 2017, 54 (1): 84-99. Consultado el 27 de junio de 2022. Disponibleen: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75072017000100008&lng=es.

  5. Montes de Oca González, A.M., González Falcón, M.,Veitia Cabarrocas, F., Lahera Fernández, E.L., Díaz López,O.B. y Hernández González, A.B., “Agrandamiento gingivalmedicamentoso en pacientes que padecen hipertensión,cardiopatías y epilepsia”, Acta Méd Centro,2021, 15 (1): 72-80. Consultado el 3 de octubre de 2023.Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2709-79272021000100072&lng=es.

  6. Koneman, E.W., Allen, S.D., Dowell, V.R., Janda, W.M.,Sommers, H.M. y Winn, W.C., Diagnóstico microbiológico,1ª reimp., México, Médica Panamericana, 1977.

  7. Sharma, U., Patel, K., Shah, V., Sinha, S., Pratap, V. y Rathores,S., “Isolation and speciation of Candida in type iidiabetic patients using chrom agar: a microbial study”,Journal of Clinical and Diagnostic Research, 2017, 11(8):dc09-dc11. doi: 10.7860/JCDR/2017/24864.10394.

  8. Hu, L., He, C., Zhao, C., Chen, X., Hua, H. y Yan, Z.,“Characterization of oral candidiasis and the Candidaspecies profile in patients with oral mucosal diseases”,Microb Pathog, 2019, 134: 103575. doi: 10.1016/j.micpath.2019.103575.

  9. Panizo, M., Reviákina, V., Flores, Y., Montes, W. y González,G., “Actividad de fosfolipasas y protesasas en aisladosclínicos de Candida spp”, Rev Soc Ven Microbiol,2005, 25 (2): 64-71. Consultado el 10 de abril de 2023.Disponible en: http://ve.scielo.org/scielo.php?script=sci_arttext&pid=S1315-25562005000200006&lng=es.

  10. Castillo, G.D.V., Blanc, S.L., Sotomayor, C.E. y Azcurra,A.I., “Study of virulence factor of Candida species in orallesions and its association with potentially malignantand malignant lesions”, Arch Oral Biol, 2018, 91: 35-41.doi: 10.1016/j.archoralbio.2018.02.012.

  11. Malani, A.N., Psarros, G., Malani, P.N. y Kauffman, C.A.,“Is age a risk factor for Candida glabrata colonisation?”,Mycoses, 2011, 54 (6): 531-537. doi: 10.1111/j.1439-0507.2010.01941. x.

  12. Patel, M., “Oral cavity and Candida albicans: colonisationto the development of infection”, Pathogens, 2022,11 (3): 335. doi: 10.3390/pathogens11030335.

  13. Fatahinia, M., Poormohamadi, F. y Zarei Mahmoudabadi,A., “Comparative study of esterase and hemolyticactivities in clinically important Candida species, isolatedfrom oral cavity of diabetic and non-diabetic individuals”,Jundishapur J Microbiol, 2015, 8 (3): e20893.doi: 10.5812/jjm.20893.

  14. Benito-Cruz, B., Aranda-Romo, S., López-Esqueda,F.J., De la Rosa-García, E., Rosas-Hernández, R. y Sánchez-Vargas, L.O., “Oral Candida isolates and fluconazolesusceptibility patterns in older Mexican women”,Arch Gerontol Geriatr, 2016, 65: 204-210. doi: 10.1016/j.archger.2016.04.001.

  15. Arslan, S., Koç, A.N., Şekerci, A.E., Tanriverdi, F., Sav,H., Aydemir, G. y Diri, H., “Genotypes and virulence factorsof Candida species isolated from oral cavities ofpatients with type 2 diabetes mellitus”, Turk J Med Sci,2016, 46 (1): 18-27. doi: 10.3906/sag-1405-73.

  16. Aguilar, D.N., Vázquez, R.M.A., “Manifestaciones bucalesen pacientes hipertensos bajo tratamiento antihipertensivo”,Arch Inv Mat Inf, 2009, 1 (2): 90-94.

  17. Otero Rey, E., Peñamaría Mallón, M., Rodríguez Piñón,M., Martín Biedma, B. y Blanco Carrión, A., “Candidiasisoral en el paciente mayor”, Avances en Odontoestomatología,2015, 31 (3): 135-148.

  18. Mothibe, J.V. y Patel, M., “Pathogenic characteristics ofCandida albicans isolated from oral cavities of denturewearers and cancer patients wearing oral prostheses”,Microb Pathog, 2017, 110: 128-134. doi: 10.1016/j.micpath.2017.06.036.

  19. Melo, A.S., Bizerra, F.C., Freymüller, E., Arthington-Skaggs,B.A. y Colombo, A.L., “Biofilm production andevaluation of antifungal susceptibility amongst clinicalCandida spp. isolates, including strains of the Candidaparapsilosis complex”, Med Mycol, 2011, 49 (3): 253-262. doi: 10.3109/13693786.2010.530032.

  20. Dantas, A., Consani, R., Sardi, J., Mesquita, M., Silva,M. y Sinhoreti, M., “Biofilm formation in denture baseacrylic resins and disinfection method using microwave”,J Res Pract Dent, 2014, 112424F.

  21. Jiménez-Beato, G. y Machuca-Portillo, G., “Heart and periodontaldiseases: does evidence exist of association?”,Med Oral Patol Oral Cir Bucal, 2005, 10 (3): 215-220.

  22. Orellana Centeno, J.E., Delgado de Alba, F.A., Nava Calvillo,J.F., Nava Zárate, N., Orellana Centeno, M. y OnofreQuilantán, M.G., “Educación y cuidado estomatológicode pacientes infantiles con insuficiencia renal en Soledadde Graciano Sánchez, San Luis Potosí”, RevistaNacional de Odontología, 2014, 8 (15): 57-62.




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Enf Infec Microbiol. 2024;44