Martínez SLM, Martínez JSI, Osorio MSI, Castañeda PS, Vásquez EV, Pamplona SAP, Rendón DM, Uribe MAM

Language: Spanish
References: 16
Page: 163-167
PDF size: 172.11 Kb.

ABSTRACT

Objective. To characterize pediatric patients with hemato-oncologic pathology and infection in a high-complexity hospital in the city of Medellin.
Methodology. Retrospective, descriptive, observational, cross-sectional study, which included pediatric patients with hemato-oncologic pathology. A non-probabilistic sampling of consecutive cases was performed. The analysis was performed in Jamovi, for quantitative variables, the mean and standard deviation or median and interquartile range were used according to their distribution. For qualitative variables, absolute and relative frequencies were used.
Results. 60 patients were included. The median age was six years, and males predominated (63.3%). The most frequent pathology was leukemia (94.9%). Regarding the source of infection, the respiratory system was the most common with 32%, followed by bacteriemia with 25%. 53.3% of patients were diagnosed with febrile neutropenia and the most frequent outcome was hospital discharge (81.7%), 16.7% died.
Conclusion. In the population studied, respiratory infections, bacteremias and gastrointestinal infections were the most frequent. Early detection and adequate management are required, taking into account the characteristics of each population.

REFERENCES

1. Abril, T., Sánchez, K., Terán, N., Aguirre, A. y Cevallos,M., “Secuelas de cáncer hematológico en niños y adolescentes:análisis fisioterapéutico”, latam, 2023, 4 (1):1640. doi: 10.56712/latam.v4i1.365.

2. Michel, G., Brinkman, T.M., Wakefield, C.E. y Grootenhuis,M., “Psychological outcomes, health-relatedquality of life, and neurocognitive functioning in survivorsof childhood cancer and their parents”, PediatrClin North Am, 2020, 67 (6): 1103-1134. doi: 10.1016/j.pcl.2020.07.005.

3. Dixon, S.B., Chen, Y., Yasui, Y., Pui, C.H., Hunger, S.P.,Silverman, L.B. et al., “Reduced morbidity and mortalityin survivors of childhood acute lymphoblastic leukemia:a report from the childhood cancer survivor study”, JClin Oncol, 2020, 38 (29): 3418-3429. doi: 10.1200/JCO.20.00493.

4. Mancero, M.J., Arellano, K., Santo, K.A. y Rodríguez,M.E., “Leucemia linfoblástica aguda, diagnostico”, Recimundo,2020, 4 (2): 53-63. doi: 10.26820/recimundo/4.(2).mayo.2020.53-63.

5. Blanco, M., Martínez, J., Patiño, D., Gil, L., Ochoa, N. ySánchez, J., “Características microbiológicas de infeccionesen pacientes pediátricos con cáncer del eje cafeterocolombiano, 2015-2016”, Rev Perú Investig Salud,2022, 6 (3): 135-140. doi: 10.35839/repis.6.3.1456.

6. Ho, K.Y., Li, W.H.C., Lam, K.W.K, Wei, X., Chiu, S.Y., Chan,C.G. et al., “Relationships among fatigue, physical activity,depressive symptoms, and quality of life in Chinesechildren and adolescents surviving cancer”, Eur J OncolNurs, 2019, 38: 21-27. doi: 10.1016/j.ejon.2018.11.007.

7. Espín JA, Camacho EA, Jurado SA, Sánchez RE, SierraVH, Abril TM,et all. Fatiga y Calidad de vida en niños,niñas y adolescentes con cáncer hematológico. Rev.Oncol. Ecu. 2021;31(1):56-65. doi: 10.33821/548

8. Liu, X., Tao, S., Ji, H., Chen, S., Gu, Y. y Jin, X., “Riskfactors for peripherally inserted central catheter (picc)-associatedinfections in patients receiving chemotherapyand the preventive effect of a self-efficacy interventionprogram: a randomized controlled trial”, Ann Palliat Med,2021, 10 (9): 9398-9405. doi: 10.21037/apm-21-1848.

9. Cataño-Toro, D., Marín-Medina, D.S., Rivera, J., Martínez,J.W., Sánchez-Duque, J.A., Martínez-Muñoz, M.A.et al., “Neutropenia febril asociada a quimioterapia enpacientes con neoplasias hematológicas de un centrode referencia en Colombia: características clínicas ydesenlaces”, Salud (Barranquilla), 2019, 35 (2): 205-220.doi: 10.14482/sun.35.2.616.15.

10. Camacho Núñez, L.P., Montenegro Martínez, G., GiraldoGallo, E. y Henao Villegas, S., “Incidencia de infeccionesasociadas a dispositivos en unidades de cuidadosintensivos adulto y pediátrica Colombia, 2012-2021”, cesMedicina, 2023, 37 (1):58-74. doi: 10.21615/cesmedicina.6950.

11. Martínez Campos, L., Pérez-Albert, P., Ferres Ramis, L.,Rincón-López, E.M., Mendoza-Palomar, N., Soler-Palacin,P. et al., “Documento de consenso de manejo de neutropeniafebril en el paciente pediátrico oncohematológicode la Sociedad Española de Infectología Pediátrica (seip)y la Sociedad Española de Hematología y OncologíaPediátrica (sehop)”, An Pediatr (Barcelona), 2023, 98 (6):446-459. doi: 10.1016/j.anpedi.2023.03.012.

12. Zhu, X., Zhang, W., Zhang, Y., Wang, Y., Hu, H., Li, J.et al., “Pegfilgrastim on febrile neutropenia in pediatricand adolescent cancer patients: a systematic reviewand meta-analysis. hematology”, 2023, 28 (1): 217-292.doi: 10.1080/16078454.2023.2172292.

13. Santolaya, M.E., Contardo, V., Torres, J.P., López-Medina,E., Rosanova, M.T., Álvarez, A.M. et al., “Manejo delos episodios de neutropenia febril en niños con cáncer.Consenso de la Sociedad Latinoamericana de InfectologíaPediátrica 2021”, Rev Chilena Infectol, 2021, 38 (6):857-909. doi: 10.4067/s0716-10182021000600857.

14. Hernández Negrete, E.L., Ruilova Gavilanes, K.M., BravoGalarza, I.P. y Ortiz Pineda, T.A., “Neutropenia febril en pacientesoncológicos pediátricos”, Reciamuc, 2021, 5 (1):130-139. doi: 10.26820/reciamuc/5.(1).ene.2021.130-39.

15. Mendoza, B. y Pineda, S., “Infección respiratoria en niñoscon cáncer en un hospital de Medellín”, Rev CubanaPediatr, 2021, 93 (1): 1-13.

16. Styczyński, J., “Complicaciones infecciosas en niños yadultos con neoplasias hematológicas”, Acta HaematolPol, 2019, 50 (3): 167-173. doi: 10.2478/ahp-2019-0027.