Merino RJA, Díaz GEJ, Rodríguez WFL

Language: Spanish
References: 10
Page: 361-365
PDF size: 235.67 Kb.

ABSTRACT

The incidence and risk factors of Clostridioides difficile infections have changed in recent decades; in Mexico, there are only a few studies on this. This study aimed to identify a possible association between previous appendectomy and the severity of C. difficile infection, which has been reported with diverse results in other investigations. We use a case-control design, with retrospective data from patients diagnosed with C. difficile over three years examined. Despite the 24% prevalence of previous appendectomy, the analysis did not reveal statistically significant differences in the severity of the infection between patients with and without this surgery. Mortality was 12%; this highlights the importance of effectively managing C. difficile infections. The results suggest that appendectomy is not associated with the severity of the infection, but factors such as oncological diagnosis and previous hospitalization could have greater relevance. In the epidemiological context of C. difficile, this study highlights the importance of effective preventive strategies and continuous improvement in the clinical management of this infection.

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