medigraphic.com
Órgano Oficial del Hospital Angeles Health System

2025, Number 1

<< Back Next >>

Acta Med 2025; 23 (1)

Neutrophil-lymphocyte index as a predictor of complicated acute appendicitis in patients at Angeles Pedregal Hospital

Sevilla SMO, Cortés RJJP, Lara GS

Language: Spanish
References: 11
Page: 24-27
PDF size: 173.91 Kb.


ABSTRACT

Introduction: acute appendicitis (AA) is the most common abdominal-surgical emergency worldwide, it has an incidence of 5.7 to 50 cases per 100,000 inhabitants with two peaks by age, at 10 and 30 years. Objective: to analyze if there is a relationship between the neutrophil-lymphocyte index and the presence of complicated acute appendicitis. Material y methods: a descriptive observational study in which 58 files of patients submitted to emergency appendectomy between January-April 2022 were analyzed. Results: the mean of the overall neutrophil-lymphocyte index and subsequently by the complicated and uncomplicated group were 9.27, 12.41, and 5.01, respectively (p = 0.0003). Conclusion: although there is a proportional relationship between neutrophil-lymphocyte index (NLI) and the presence of complicated acute appendicitis, there is no validated cut-off point, and therefore, its routine use cannot be recommended.


REFERENCES

  1. García-Amador C, Arteaga Peralta V, de la Plaza Llamas R, Torralba M, Medina Velasco A, Ramia JM. Valoración de parámetros clínicos y analíticos preoperatorios en apendicitis aguda complicada. Score para predecir apendicitis complicada. Cir Esp [Internet]. 2021; 99 (4): 282-288. Disponible en: https://www.elsevier.es/es-revista-cirugia-espanola-36-articulo-valoracion-parametros-clinicos-analiticos-preoperatorios-S0009739X20302050

  2. Shen G, Li S, Shao Z, Liu L, Liu Q, Yu H et al. Platelet indices in patients with acute appendicitis: a systematic review with meta-analysis. Updates Surg [Internet]. 2021; 73 (4): 1327-1341. Available in: https://pubmed.ncbi.nlm.nih.gov/33439467/

  3. Godínez-Vidal AR, Sashida-Méndez H, Cruz-Romero CI, Bandeh-Moghaddam H, Gutiérrez-Banda CA, Gracida-Mancilla NI. Comparación del índice de neutrófilos/linfocitos, la escala de SOFA y la concentración sérica de procalcitonina como indicadores de la gravedad de la apendicitis aguda. Cir Cir [Internet]. 2018; 87 (1): 12-17. Disponible en: https://pubmed.ncbi.nlm.nih.gov/30600800/

  4. Delgado-Miguel C, Muñoz-Serrano AJ, Barrena Delfa S, Núñez Cerezo V, Estefanía K, Velayos M et al. Índice neutrófilo-linfocito como predictor de peritonitis en apendicitis aguda en niños. Cir Pediatr [Internet]. 2019; 32: 185-189. Disponible en: https://www.secipe.org/coldata/upload/revista/2019_32-4_185-189.pdf

  5. Ribeiro AM, Romero I, Pereira CC, Soares F, Goncalves A, Costa S et al. Inflammatory parameters as predictive factors for complicated appendicitis: a retrospective cohort study. Ann Med Surg [Internet]. 2022; 74: 103266. Available in: https://www.sciencedirect.com/science/article/pii/S2049080122000267

  6. Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A et al. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines. World J Emerg Surg. 2020; 15 (1): 27. doi: 10.1186/s13017-020-00306-3.

  7. Hajibandeh S, Hajibandeh S, Hobbs N, Mansour M. Neutrophil-to-lymphocyte ratio predicts acute appendicitis and distinguishes between complicated and uncomplicated appendicitis: A systematic review and meta-analysis. Am J Surg [Internet]. 2020; 219 (1): 154-163. Available in: https://pubmed.ncbi.nlm.nih.gov/31056211/

  8. Halaseh SA, Kostalas M, Kopec CA, Nimer A. Single-center retrospective analysis of neutrophil, monocyte, and platelet to lymphocyte ratios as predictors of complicated appendicitis. Cureus. 2022; 14 (9): e29177. Available in: https://pubmed.ncbi.nlm.nih.gov/36259022/

  9. Saltiel D. Apendicitis aguda. En: morales J. Tratado de cirugía general. 3a ed. México: Manual Moderno; 2017. pp. 1222-1228.

  10. Haak F, Kollmar O, Ioannidis A, Slotta JE, Ghadimi MB, Glass T et al. Predicting complicated appendicitis based on clinical findings: the role of Alvarado and appendicitis inflammatory response scores. Langenbecks Arch Surg [Internet]. 2022; 407 (5): 2051-2057. Available in: http://dx.doi.org/10.1007/s00423-022-02533-5

  11. Andersson M, Kolodziej B, Andersson RE. Validation of the appendicitis inflammatory response (AIR) score. World J Surg [Internet]. 2021; 45 (7): 2081-2091. Available in: http://dx.doi.org/10.1007/s00268-021-06042-2




2020     |     www.medigraphic.com