Flores MDN, Jaramillo SAE, Pizaña DA

Language: Spanish
References: 16
Page: 604-608
PDF size: 271.99 Kb.

ABSTRACT

Introduction: malnutrition is a highly prevalent condition in the intensive care unit and a negative prognostic factor, as it increases mortality and hospital length of stay. On the other hand, the neutrophil-to-lymphocyte ratio has been shown to be an independent predictor of mortality and prognosis in various inflammatory and infectious diseases, serving as a sensitive indicator in inflammatory processes with high predictive and validated prognostic value. Objective: to analyze the performance of the neutrophil/lymphocyte index in comparison with the nutritional risk assessed by the modified Nutric score scale in critically ill patients admitted to the Intensive Care Unit of the Ángeles Mocel Hospital of the Ángeles Health System group in Mexico City. Material and methods: analytical, descriptive, retrospective, cross-sectional study in the period from March 1, 2023 to February 29, 2024. The inclusion criteria were critically ill patients who were admitted to the intensive care unit. Results: 154 files were analyzed, of which 24 were excluded due to not having complete data and only 130 were included in the study. Of the total number of patients, 53.1% were female. 9.2% of the study population died and 90.8% were discharged due to clinical improvement. The correlation of the neutrophil/lymphocyte index with the modified Nutric score scale was r = 0.295 and p = 0.001. The cut-off point for the neutrophil-lymphocyte index of 6.7 × 10³/μL was determined using the median with an accuracy of 55%, with a sensitivity of 52.8%, specificity of 65.3%, positive predictive value of 85.9 and predictive value negative of 25.7. Through the ROC curve analysis, the cut-off point for the neutrophil/lymphocyte index was obtained as 2.05 with sensitivity of 90.7% and specificity of 91.7%. Conclusion: this study did not show a difference in the value of the neutrophil/lymphocyte ratio, so this index is not a biomarker that can be associated with the increased risk of malnutrition in critically ill patients.

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