Cienfuegos MR, Sierra ME, Juárez AE, Kuri HW

Language: Spanish
References: 6
Page: 84-88
PDF size: 76.80 Kb.

ABSTRACT

This paper describes a study, carried out at the Hospital de Traumatología y Ortopedia “Lomas Verdes” in Mexico City, on the use of frozen cultured human-epidermis allografts over donor skin sites and meshed autografts in patients with lower limb fractures who required early reconstruction of the skin cover. Meshed autografts were placed upon a gastrocnemius medialis flap or upon the muscle mass left uncovered after performing a fasciocutaneous flap, and covered with cultured epidermis allografts. In these lesions, cultured epidermal allografts stimulated re-epitelization of the interstices in the mesh within six days of surgery. Results showed a faster re-epithelization of donor sites treated with frozen cultured human epidermis allografts compared to control areas; cultured epidermal allografts reduced 60% the time to epithelization. These results suggest that, aside from the treatment of burns, frozen cultured human epidermis allografts may be used routinely in the treatment of patients with fracture-induced soft-tissue injuries.

REFERENCES

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