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Alergia, Asma e Inmunología Pediátricas

Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría
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2006, Number 3

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Alerg Asma Inmunol Pediatr 2006; 15 (3)

Presentation of antigens

J Alonso Gutiérrez Hernández, Marco A Yamazaki Nakashimada, José G Huerta López
Full text How to cite this article

Language: Spanish
References: 7
Page: 90-93
PDF size: 196.11 Kb.


Key words:

Antigens, multicellular microorganisms, specific immune response, interactions.

ABSTRACT

One of the most advanced functions in multicellular microorganisms is the immune system. This system has evolved simultaneously with these organisms. This response has two elementary components: one of them is innate, presenting a quick and general response and a very specific response. In this last case it is required that a more elaborated process takes place in order to create a very sensitive response specially directed to each aggression in a very peculiar form. The presentation of antigens represents the middle point between both responses, capturing antigens in very strategic points in a very early stage and collaborating with the specific immune response to generate a very complete blocking. Following, it is performed a very didactic analysis in order to explain these interactions.


REFERENCES

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  2. Houde M, Bertholet S et al. Phagosomes are competent organelles for antigen Cross-presentation. Nature 2003; 425: 402.

  3. Honey K. Dcs spot the difference. Nature Reviews Immunology 2006; 6: 1.

  4. Blander JM, Medzhitov R. Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature 19 Feb 2006 (Doi:10.1038/Nature04596).

  5. Ben-Neriah Y. Regulatory functions of ubiquitination in the immune system. Nature Immunology 2002; 3(1): 20-26.

  6. Petroski MD, Deshaies RJ. Function and regulation of Cullin-ring ubiquitin ligases. Nature Reviews 2005; 6: 9-20.

  7. Van Rhijn I, Zajonc DM et al. T-cell activation by lipopeptide antigens. Current Opinion In Immunology 2005; 17: 222-229.




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C?MO CITAR (Vancouver)

Alerg Asma Inmunol Pediatr. 2006;15