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ISSN 1561-3119 (Electronic)

2022, Number 3

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Rev Cubana Pediatr 2022; 94 (3)

Type 1 diabetes mellitus and celiac disease in children and adolescents

Véliz JAL, Araujo HO, Ávila OI

Language: Spanish
References: 28
Page: 1-15
PDF size: 433.89 Kb.


ABSTRACT

Introduction: The association between celiac disease and type 1 diabetes mellitus has been published more frequently than isolated celiac disease, whose natural history can vary considerably, with evidence of gastrointestinal symptoms in the minority of patients.
Objective: To characterize patients with type 1 diabetes mellitus and celiac disease.
Method: Observational, descriptive and cross-sectional study in 63 children treated at "Centro Habana" Pediatric Teaching Hospital between the years 2016-2017 with a diagnosis of type 1 diabetes mellitus. The variables studied were expressed in absolute and relative values, a measure of central tendency and dispersion.
Results: Males accounted for 58.73% of the patients, most of them between 10 and 14 years old. The anti-transglutaminase antibody was positive in less than 10% of the children, usually without symptoms, signs, or findings related to celiac disease. The frequency of both diseases in the patients studied was 3.17%.
Conclusions: Type 1 diabetes mellitus predominates in males unlike celiac disease which is diagnosed in female patients. The results of anti-transglutaminase antibodies are negative in most patients while the positive ones have more than a year of evolution of diabetes, are eutrophic or overweight, asymptomatic and with slightly higher values of glycosylated hemoglobin.


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