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2022, Number 4

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Rev Cubana Pediatr 2022; 94 (4)

Linear IgA dermatosis of childhood induced by cephalosporin

Fernández YG, Castillo NNA, Casas GAH, Gándara CYW
Full text How to cite this article

Language: Spanish
References: 10
Page: 1-9
PDF size: 336.82 Kb.


Key words:

linear IgA dermatosis, childhood, cephalosporin.

ABSTRACT

Introduction: Linear IgA dermatosis is a rare blistering disorder, which mainly affects children under 5 years of age and is characterized by IgA deposits in the dermoepidermal basement membrane. It presents with tense blisters that are usually located in the perioral and perineal area.
Objective: To describe linear IgA dermatosis in childhood induced by cephalosporins.
Case Presentation: 2-year-old boy, phototype III, who developed a vesicle-blister rash after treatment with cephalosporins for a skin infection. Due to its characteristic clinical presentation and findings in histopathology and direct immunofluorescence it is diagnosed as linear IgA dermatosis.
Conclusions: Linear IgA dermatosis is a rare disease. It is known that in the last 20 years only 4 cases have been diagnosed in Cuba, so it is important to have this fact present at the time of raising possible causes of bullous dermatoses, for early intervention. It is important to note that it can be manifested by exposure to drugs as happened in this case.s


REFERENCES

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  2. Juratli HA, Sárdy M. Lineare IgA-Dermatose. Hautarzt. 2019;70:254-9. DOI: http://doi.org/10.1007/s00105-019-4377-92.

  3. Carlos E, Dimatos OC, Porro AM, Santi CG. Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis. Brazilian Soc Dermatol. 2019;94:48-55. DOI: 10.1590/abd1806-4841.2019940208

  4. Stamenkovic HM, Lazarevic D, Stankovic T, Vojinovic J, Lekic B, Marinkovic A, et al. Linear IgA dermatosis of the childhood-Report of an amoxicillin-induced case. Dermatol Ther. 2019:2-5. DOI: 10.1111/dth.13173

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  8. Solak SS. Cephalosporin-induced linear IgA dermatosis in a child: Case report and literature review. Dermatol Ther. 2019;32(4)e12927. DOI: 10.1111/dth.12927

  9. Yuri T, Machado S, Iida TM, Iru H, Àuvw WKH, Lq W, et al. Adult linear IgA bullous dermatosis: report of three cases An Bras Dermatol. 2018;93(3):435-7. DOI: http://dx.doi.org/10.1590/abd1806-4841.201873049.

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Rev Cubana Pediatr. 2022;94