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2025, Number 1

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Lat Am J Oral Maxillofac Surg 2025; 5 (1)

Mucoepidermoid carcinoma of the parotid gland: diagnosis, surgical and adjuvant treatment. Review of the literature

Fajardo S, Crespo P, Salgado-Chavarría F

Language: Spanish
References: 13
Page: 7-10
PDF size: 215.85 Kb.


ABSTRACT

Introduction: mucoepidermoid carcinoma (MEC) is considered the most common malignant neoplasm in the salivary glands, with a prevalence of between 30 and 40%. Material and methods: a search was carried out in the databases: PubMed, ScienceDirect and Elsevier. Using the search words, obtaining 202 articles, then the analysis was carried out and applying the inclusion and exclusion criteria, 13 articles were obtained for the final analysis. Results: the female sex was affected in 53.34%. The maximum size of mucoepidermoid carcinoma was 4 cm. According to the histological presentation, around 53.8% were low grade. The five-year disease-free survival rate was 98, 97, and 67% in low-, intermediate-, and high-grade cases, respectively. In the high-grade group, cases with recurrence were found to have a higher rate of local lymph node metastases. In none of the cases of recurrence was there expression of the MECT 1-MAML2 gene. The treatment of choice was complete resection with regular surgical margin. Conclusion: mucoepidermoid carcinoma is the most common malignant neoplasm of the salivary glands, it affects more women, from the second to the ninth of life. According to its histopathological characteristics, low grade is the most common. Surgical excision with safety margins is usually sufficient; in cases with metastasis to the cervical nodes, lymphadenectomy is necessary. The five-year disease-free survival rate is higher for low and intermediate grades.


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