Jiménez GCY, González PN, López CL, Domínguez FOY, Almaraz RJ, Camacho AHC

Language: Spanish
References: 9
Page: 632-635
PDF size: 314.99 Kb.

ABSTRACT

Introduction: in patients with severe acute respiratory distress syndrome (ARDS) due to SARS-COV-2, the clinical course seems to be influenced by altitude acclimatization. Material and methods: observational, retrospective, longitudinal, comparative study in patients with severe ARDS due to SARS-CoV-2. The degree of tomographic involvement, days of mechanical ventilation (MV), days of stay in the intensive care unit (ICU), days of hospitalization and probability of survival in natives of low, medium and high altitudes were analyzed. Results: natives of low and medium altitudes required 4.3 more days of MV, 4.2 more days of stay in the ICU and 2.6 more days of hospital stay when compared with those acclimatized to high altitude (p = 0.286, p = 0.302, p = 0.893 respectively). Severe CT involvement occurred in 100% of patients native to low and medium altitude vs 71.4% of those native to high altitude (p = 0.159). Survival in natives of low, medium and high altitude was 50, 62.5 and 68% respectively (p = 0.872). Conclusion: patients acclimatized to high altitude with severe ARDS due to SARS-CoV-2 tend to have a more favorable clinical course with higher survival when compared to natives of lower altitude.

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