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ISSN 1405-0099 (Print)

2025, Number 2

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Cir Gen 2025; 47 (2)

Primary extragonadal teratoma in the greater omemtum

Ramírez AJR, Cruz ZR

Language: Spanish
References: 17
Page: 99-103
PDF size: 309.80 Kb.


ABSTRACT

Introduction: teratomas are neoplasms derived from totipotent germ cells, capable of differentiating into tissues from the three germ layers: ectoderm, mesoderm, and endoderm. Although most are located in the gonads, less than 5% develop in extragonadal sites, with the greater omentum being an exceptionally rare location. This rarity makes them clinically significant due to their low incidence and distinctive characteristics. Case report: we report the case of a 49-year-old woman with a chronic abdominal mass. Imaging studies, including ultrasound and contrast-enhanced computed tomography, revealed a predominantly cystic, encapsulated mass without signs of invasion or malignancy. Tumor marker levels, such as CA-125 and alpha-fetoprotein, were within normal ranges. During exploratory laparotomy, a lesion was found adhered to the greater omentum, containing sebaceous material, hair, and teeth. Histopathological analysis confirmed a mature monodermal teratoma (struma ovarii). Complete surgical excision was performed, along with a left salpingo-oophorectomy due to an associated ovarian cyst. Conclusion: this case highlights the importance of an interdisciplinary approach, clinico-pathological correlation, and complete surgical excision as the definitive treatment for rare neoplasms.


REFERENCES

  1. Shin S, Choi Y, Jung S, Chung Y, Lee S. Single cell gene transcriptome analysis of ovarian mature teratomas. Pathol Oncol Res. 2021; 27: 604228. doi: 10.3389/pore.2021.604228.

  2. Rampinelli F, Donarini P, Visenzi C, Ficarelli S, Gambino A, Ciravolo G. The rare extragonadal omental teratoma: a case report. J Minim Invasive Gynecol. 2017; 24: 1046-1048. doi: 10.1016/j.jmig.2017.05.022.

  3. Ojea Calvo A, Rodríguez Alonso A, Pérez García D, Domínguez Freire F, Alonso Rodrigo A, Rodríguez Iglesias B, et al. Tumor extragonadal de células germinales con fenómeno "burned-out" en testículo. Actas Urol Esp. 1999; 23: 880-884. doi: 10.1016/S0210-4806(99)72389-2.

  4. Gupta V, Garg H, Lal A, Vaiphei K, Benerjee S. Retroperitoneum: a rare location of extragonadal germ cell tumour. Internet J Surg [Internet]. 2007; 17. Available in: http://www.ispub.com/IJS/17/2/6693

  5. Patel S, Kunnath AJ, Gallant JN, Belcher RH. Surgical management and outcomes of pediatric congenital head and neck teratomas: a scoping review. OTO Open. 2023; 7: e66. doi: 10.1002/oto2.66.

  6. Yang Y, Zhao M, Chen M, Tang H, Qin Z, Liu J, et al. Mature cystic extragonadal teratoma in Douglas' pouch: Case report and literature review. Front Med (Lausanne). 2023; 9: 985235. doi: 10.3389/fmed.2022.985235.

  7. Lee KH, Song MJ, Jung IC, Lee YS, Park EK. Autoamputation of an ovarian mature cystic teratoma: a case report and a review of the literature. World J Surg Oncol. 2016; 14: 217. doi: 10.1186/s12957- 016-0981-7.

  8. Kim HG, Song YJ, Na YJ, Yang J, Choi OH. A rare case of an autoamputated ovary with mature cystic teratoma. J Menopausal Med. 2017; 23: 74-76. doi: 10.6118/jmm.2017.23.1.74.

  9. Varras M, Akrivis CH, Plis CH, Tsoukalos G. Antenatal sonographic diagnosis of pharyngeal teratoma: our experience of a rare case with review of the literature. Obstet Gynecol Int. 2009; 2009: 180643. doi: 10.1155/2009/180643.

  10. Gunasekaran S, Kopecka E, Maung KH, England RJ. Struma ovarii and the thyroid surgeon. J Laryngol Otol. 2012; 126: 858-860. doi: 10.1017/S0022215112000904.

  11. Wani BN, Rathod V, Banode P, Bhole A. An omental teratoma in a young girl. Clin Pract. 2011; 1: e129. doi: 10.4081/cp.2011.e129.

  12. Arenas JC, Romo JA, López LA. Teratoma extragonadal del omento mayor, una localización poco usual: reporte de caso y revisión de la literatura. Rev Colomb Cir. 2020; 35: 689-694.

  13. Feng F, Tian Y, Xu G, Liu Z, Liu S, Zheng G, et al. Diagnostic and prognostic value of CEA, CA19-9, AFP and CA125 for early gastric cancer. BMC Cancer. 2017; 17: 737. doi: 10.1186/s12885-017-3738-y.

  14. Moraru L, Mitranovici MI, Chiorean DM, Coros M, Moraru R, Oala IE, et al. Immature teratoma: diagnosis and management—A review of the literature. Diagnostics. 2023; 13: 1516. doi: 10.3390/diagnostics13091516.

  15. Belayachi B, Fenane H, Msougar Y. Surgical management of mediastinal mature cystic teratoma of the elderly remaining asymptomatic. J Cardiothorac Surg. 2024; 19: 28. doi: 10.1186/s13019-024-02503-6.

  16. Kudva R, Monappa V, Rai L. Placental teratoma: a diagnostic dilemma with fetus acardius amorphous. Indian J Pathol Microbiol. 2010; 53: 378-379.

  17. Miyamura T, Itakura M, Miyazaki T, Fujii Y, Hori S, Nakao S, et al. A case of malignant struma ovarii diagnosed after laparoscopic surgery. J Showa Univ Soc. 2023; 83: 57-62. doi: 10.14930/jshowaunivsoc.83.57.




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