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2025, Number 1

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Med Crit 2025; 39 (1)

Sociodemographic factors, comorbidities and sepsis: the dark side of the moon

Ávila-Hilari A, Burgoa-Apaza R, Saravia-Quispe RL, Aguilera-Enriquez XS, Avellanas-Chavala ML

Language: Spanish
References: 34
Page: 19-24
PDF size: 253.49 Kb.


ABSTRACT

Introduction: sepsis is a complex infectious disease that represents a burden in terms of morbidity, mortality and financial costs for healthcare systems. Objective: to demonstrate that sociodemographic factors and comorbidities mark the difference in mortality between developed countries with resources and developing countries with low resources. Design: observational, retrospective, analytical and cross-sectional study. Setting: multidisciplinary Intensive Care Unit (ICU) in a Hospital in Bolivia. Patients: adults admitted over 18 years old who were admitted to the ICU for two consecutive years who met the Sepsis-3 criteria. Main variables of interest: morbidity, mortality and sociodemographic and comorbidity variables associated with sepsis. Results: a total of 186 patients were admitted, 119 (64%) had sepsis, and the mortality rate among them was 51%. The most frequent etiology was pulmonary (48.7%). Sixty-four percent of the patients had no income, 37% had no access to education and 62% were unemployed. The comparative analysis between outcomes (living patients versus deceased patients) was statistically significant in all variables (p < 0.001), except gender. The identification of factors independently associated with mortality was significant in all sociodemographic variables, but respiratory failure was the only significant comorbidity. Conclusions: scarcity of economic resources, lack of work, age > 60 years, lack of education and the presence of comorbidities severely impact on mortality from sepsis.


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