2025, Number 5
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Rev ADM 2025; 82 (5)
Pulp regeneration with stem cells and bioactive scaffolds: a glimpse into the future of endodontics.
Morales VGA, Chicaiza BKV, Salazar VKV, Yaguachi GMÁ, Yánez VMG, Larco ZJM
Language: Spanish
References: 32
Page: 283-290
PDF size: 406. Kb.
ABSTRACT
Introduction: in the last 15 years, dental research has advanced in the regeneration and replacement of damaged dental tissues through root canal restoration procedures. Tissue engineering, based on stem cells, biomaterials, and bioactive molecules, is revolutionizing treatments in endodontics and periodontics, promoting dental and maxillofacial regeneration.
Objective: the objective of this study is to review pulp regeneration strategies using stem cells and bioactive scaffolds, analyzing their potential in the future of endodontics to restore damaged dental tissues and promote pulp tissue regeneration.
Material and methods: the information search was conducted in the databases EBSCO Dentistry & Oral Sciences Source, Science Direct, and Google Scholar, using keywords related to pulp regeneration, stem cells, bioactive scaffolds, and endodontics.
Results: the literature review showed advances in pulp regeneration with stem cells and bioactive scaffolds, promoting tissue revitalization and root development. Biomaterials favor biomineralization and better long-term outcomes compared to conventional treatments, although further research is needed to optimize their effectiveness.
Conclusions: pulp regeneration using stem cells and bioactive scaffolds represents an advancement in modern endodontics, offering conservative and biological treatments to restore pulp tissue vitality. Although the results are promising, more research is needed to standardize protocols and validate their clinical effectiveness in the long term.
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