2025, Number 2
Analysis of morbidity and mortality of diabetic ketoacidosis in a Second Level Hospital in Mexico
Language: Spanish
References: 15
Page: 111-114
PDF size: 243.24 Kb.
ABSTRACT
Introduction: Diabetic ketoacidosis is a very common condition that presents as an acute complication of diabetes mellitus, characterized by hyperglycemia, metabolic acidosis, and ketosis. Acute complications of diabetes represent a high percentage of admissions to the emergency department of secondary care hospitals in Mexico. Material and methods: A retrospective, observational, comparative, cohort, and descriptive study using a documented analysis technique. Information was obtained from a logbook from the Intensive Care Unit of our hospital, and all patients older than 14 years of age diagnosed with diabetic ketoacidosis were included. Subjects younger than 14 years of age and those with hyperosmolar states were excluded. Results: Of the 1,725 ??patients admitted to the Intensive Care Unit, only 134 presented diabetic ketoacidosis; 91% of these were of metabolic origin. Three patients presented acute pancreatitis, and complications accounted for 0.7% of the cases, including acute kidney injury, urosepsis, preeclampsia, and pneumonia. The most common age group was 20 to 30 years, while mortality was 10%. The incidence of diabetic ketoacidosis was more common in males, in contrast to the study by Li et al., which reported a predominance in females. Regarding the age group, we agree with Ramphul et al., who determined a mean age of 18 to 44 years in the US population. Therefore, we took into account that our caseload in Mexico is partially similar and that the trend of diabetic ketoacidosis has been higher in the male population, as well as a higher mortality rate. Conclusions: In this study of patients with diabetic ketoacidosis, incidence and mortality tend to increase in our hospital and are related to economic and sociocultural factors given that our country is developing.REFERENCES
Li L, Andrews EB, Li X, Doder Z, Zalmover E, Sharma K, et al. Incidence of diabetic ketoacidosis and its trends in patients with type 1 diabetes mellitus identified using a U.S. claims database, 2007-2019. J Diabetes Complications. 2021;35(7):107932. Available in: https://www.sciencedirect.com/science/article/pii/S1056872721001100
Ramphul K, Joynauth J. An update on the incidence and burden of diabetic ketoacidosis in the U.S. diabetes care. 2020;43(12):e196-e197. doi: 10.2337/dc20-1258. Epub 2020 Oct 13. Erratum in: Diabetes Care. 2022;45(7):1698. Available in: https://diabetesjournals.org/care/article/43/12/e196/31050/An-Update-on-the-Incidence-and-Burden-of-Diabetic
Domínguez RM, Calderón MMA, Matías AR. Características clínico epidemiológicas de las complicaciones agudas de la diabetes en el servicio de urgencias del Hospital General de Atizapán. Rev Fac Med (Méx). 2013;56(2):25-36. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0026-17422013000600004