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2023, Number 1

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Correo Científico Médico 2023; 27 (1)

Morphometric features of the endometrial epithelium in patients with endometriosis

Jorge SY, Morales RI, Díaz RPA

Language: Spanish
References: 16
Page:
PDF size: 269.82 Kb.


ABSTRACT

Introduction: Any finding of functional endometrium in a place other than intrauterine is named endometriosis. This disease is a concern, since it is difficult to diagnose and involves a number of specialties for its investigation.
Objective: To characterize morphometric indicators of endometrial epithelium in biopsies from patients with internal endometriosis (adenomyosis).
Method: Histological preparations of 37 biopsies diagnosed with internal endometriosis in the Department of Pathological Anatomy of the "Vladimir Ilich Lenin" Hospital of Holguin, Cuba, in the period from 2013 2019, were studied. Morphometric parameters, area, density, glandular height and area, volume and nuclear form factor were determined. Morphometric indicators using the computer application ImageJ Version 1.49p from the National Institute of Health, USA, 2015, were measured. The results were processed with the professional statistical editor MyStat version 12. The arithmetic value, standard deviation, coefficient of variation, and confidence interval were calculated, for 95% of certainty.
Results: The presence of endometrial tissue was found between the muscular fascicles of the myometrium. The ratio (density) represents 7% of the total area of the myometrium, the height of the epithelium corresponds to the endometrial glands in healthy patients, in the nuclear area and volume there was no variability, but in the shape factor the nuclei showed morphological changes.
Conclusions: The existence of a nuclear pleomorphism compatible with the diagnosis of adenomyosis in these patients was proved.


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